{"id":"W4413734272","doi":"10.33540/3174","title":"Unmet needs in T cell-based cancer therapies: opportunities for translational innovation","year":2025,"lang":"en","type":"dissertation","venue":"","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Translational science; Translational research; Medicine; Oncology; Cancer research; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01755507,0.001184749,0.001813539,0.001519279,0.001674623,0.007791451,0.001954338,0.01244875,0.02202917],"category_scores_gemma":[0.006791739,0.0004747484,0.001442667,0.001580334,0.0065009,0.01374556,0.004639597,0.0108363,0.005881203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0028833,"about_ca_system_score_gemma":0.01492504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008260711,"about_ca_topic_score_gemma":0.001830824,"domain_scores_codex":[0.9960173,0.001266029,0.0002864378,0.0004189479,0.001015105,0.0009962588],"domain_scores_gemma":[0.9871975,0.005606905,0.0006693338,0.0006174139,0.002101852,0.003807027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0007983709,0.001060476,0.001041787,0.007230732,0.0001411834,0.0008500321,0.001217537,0.002655687,0.008136913,0.1854854,0.2386801,0.5527018],"study_design_scores_gemma":[0.0002931439,0.001082786,0.001310189,0.004012377,0.00007109941,0.0007830067,0.003545699,0.002335737,0.001429129,0.2890227,0.6960061,0.0001080673],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.003596364,0.4698,0.007601456,0.4992332,0.009127791,0.0000632747,0.0002360762,0.0002577844,0.01008408],"genre_scores_gemma":[0.05203326,0.7955051,0.024148,0.08756777,0.02832292,0.0003131421,0.0005747048,0.0001189888,0.01141603],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.02202917,"threshold_uncertainty_score":0.09284121,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1140093159602814,"score_gpt":0.3894417403053376,"score_spread":0.2754324243450563,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}