{"id":"W4413756294","doi":"10.1021/acsomega.5c00702","title":"Synthesis of Metformin Hydrosulfide and Its Controlled-Release of H<sub>2</sub>S","year":2025,"lang":"en","type":"article","venue":"ACS Omega","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Sodium hydrosulfide; Metformin; Chemistry; Internal medicine; Hydrogen sulfide; Medicine; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001093197,0.0003056236,0.0001734123,0.0001456919,0.0001542348,0.000128139,0.0002372418,0.0002513557,0.001693944],"category_scores_gemma":[0.00009042609,0.0001495803,0.0001702293,0.0001306732,0.0001104728,0.0001873489,0.0001423317,0.0002970712,0.000770534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001974211,"about_ca_system_score_gemma":0.000165089,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002966543,"about_ca_topic_score_gemma":0.0006446581,"domain_scores_codex":[0.9999293,0.000004889295,0.000005363207,0.00001666836,0.00003262576,0.00001104962],"domain_scores_gemma":[0.9999549,0.000004348782,0.00001547085,0.000005480118,0.000009872098,0.000009809398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002653219,0.000005205112,0.0000255872,0.00002905015,0.000001831881,0.00003263972,0.000005697251,0.00005025245,0.998114,0.00007154528,0.0000497021,0.001587993],"study_design_scores_gemma":[0.000005734585,0.00007189589,0.0003396492,0.000001519885,0.000002818658,0.00004264637,0.000004222377,0.0002636565,0.9967242,0.000009171972,0.0025317,0.0000029084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9689267,0.002515461,0.01851942,0.0001839566,0.0001529481,0.000318425,0.001235175,0.0003996732,0.007748179],"genre_scores_gemma":[0.9515584,0.002418303,0.03263541,0.0000920556,0.00004803957,0.0002711743,0.001123897,0.0001265874,0.01172605],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001693944,"threshold_uncertainty_score":0.005666792,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006506795440353114,"score_gpt":0.2354046602609931,"score_spread":0.22889786482064,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}