{"id":"W4413757473","doi":"10.3390/cancers17172804","title":"Anti-EGFR Therapy in Metastatic Colorectal Cancer: Identifying, Tracking, and Overcoming Resistance","year":2025,"lang":"en","type":"review","venue":"Cancers","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Moncton; BC Cancer Agency","funders":"","keywords":"Colorectal cancer; Medicine; Oncology; Cancer; Internal medicine; Cancer research; Bioinformatics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005990406,0.000375952,0.0005975068,0.0005312987,0.0001667135,0.0007847905,0.0003590403,0.0005767329,0.0007056019],"category_scores_gemma":[0.0006330355,0.0001293546,0.0002512127,0.0003838101,0.0004127912,0.0005685778,0.0003535101,0.001107625,0.0003742542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009328689,"about_ca_system_score_gemma":0.0006465479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009630618,"about_ca_topic_score_gemma":0.002422391,"domain_scores_codex":[0.9997261,0.00008208837,0.00001459188,0.0000390955,0.0001003088,0.00003780196],"domain_scores_gemma":[0.9997815,0.00005781564,0.00004047112,0.00001524466,0.00005977213,0.00004502866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009798501,0.0003696316,0.006543619,0.002379074,0.00009734582,0.0009186554,0.0001416448,0.002696649,0.102748,0.005455466,0.01670718,0.8609629],"study_design_scores_gemma":[0.0008978699,0.01301779,0.06979113,0.002238434,0.0006260937,0.02695682,0.0005612343,0.03124689,0.1659463,0.01594645,0.6725426,0.0002283923],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1585023,0.7912606,0.01586206,0.02173569,0.001007766,0.0001652261,0.0002373871,0.0005947456,0.01063406],"genre_scores_gemma":[0.6506898,0.3234501,0.01314167,0.005748045,0.001219006,0.0001299779,0.0003930663,0.00005293789,0.00517548],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0009630618,"threshold_uncertainty_score":0.006768465,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06817939000674166,"score_gpt":0.3940341325024812,"score_spread":0.3258547424957395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}