{"id":"W4413757518","doi":"10.3390/cells14171326","title":"Cardiac Cell and Animal Models for Duchenne Muscular Dystrophy in the Era of Gene Therapy and Precision Medicine","year":2025,"lang":"en","type":"review","venue":"Cells","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"Muscular Dystrophy Canada; University of Alberta; Canadian Institutes of Health Research; Parent Project Muscular Dystrophy; Faculty of Medicine and Dentistry, University of Alberta; Foundation to Eradicate Duchenne; Women and Children's Health Research Institute; Children's Health Research Institute; Heart and Stroke Foundation of Canada; U.S. Department of Defense","keywords":"Duchenne muscular dystrophy; Muscular dystrophy; Medicine; Genetic enhancement; Precision medicine; Cardiology; Bioinformatics; Internal medicine; Gene; Pathology; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002704314,0.000208874,0.000652451,0.00004024807,0.00003485363,0.000004676536,0.0001644297,0.0002765462,0.000002276564],"category_scores_gemma":[0.00001802689,0.0001289802,0.0001610811,0.00006849875,0.0001284322,0.000001979643,0.00005077554,0.0001254231,1.401817e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002850439,"about_ca_system_score_gemma":0.00006560181,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001464315,"about_ca_topic_score_gemma":0.000001059047,"domain_scores_codex":[0.9990382,0.0001638452,0.0002551521,0.0003504989,0.00005525259,0.0001371136],"domain_scores_gemma":[0.9994095,0.0001179773,0.0001086527,0.0003038388,0.00003427055,0.00002576767],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003928993,0.0001732241,0.000004259653,0.01449571,0.0002748421,0.000001926065,0.0003059996,0.00004000006,0.116547,0.000186774,0.002635117,0.8649423],"study_design_scores_gemma":[0.002113375,0.001820738,0.00005247426,0.00219509,0.0005533025,0.00000300576,0.0001405136,0.00005857418,0.008979844,0.001001089,0.9825616,0.0005203972],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01155252,0.9870131,0.000195658,0.00002328848,0.00007432589,0.0008620302,0.00006747543,0.000001494057,0.0002101151],"genre_scores_gemma":[0.005172746,0.9941022,0.0002162805,0.00006200401,0.00009586622,0.00009807688,0.0001954607,0.00001348084,0.00004391712],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9799265,"threshold_uncertainty_score":0.5259658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02015833305442678,"score_gpt":0.2832175687914176,"score_spread":0.2630592357369909,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}