{"id":"W4413766723","doi":"10.21203/rs.3.rs-7348924/v1","title":"Metastatic Castration-Resistant Prostate Cancer: 14-Year Real-World Sipuleucel-T Outcomes in Urology","year":2025,"lang":"en","type":"preprint","venue":"Research Square","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Associated Medical Services","funders":"Dendreon Pharmaceuticals","keywords":"Prostate cancer; Medicine; Urology; Castration; Oncology; Internal medicine; Cancer; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001247876,0.0004547173,0.0006287885,0.0007968085,0.0004455774,0.00177508,0.0007862445,0.0006306532,0.004020099],"category_scores_gemma":[0.005327855,0.0001963222,0.001185581,0.00158384,0.000493849,0.001387464,0.001812217,0.0009936425,0.0008483749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008929427,"about_ca_system_score_gemma":0.001137656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01576467,"about_ca_topic_score_gemma":0.01381614,"domain_scores_codex":[0.9994399,0.0001355639,0.0000366965,0.000120734,0.0001160413,0.0001510403],"domain_scores_gemma":[0.9981319,0.0003067846,0.0006031883,0.0001572005,0.0002313546,0.0005696185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001595647,0.0001417477,0.9743913,0.0001154276,0.0004674438,0.0001446297,0.0002656193,0.0008959886,0.000095007,0.0002429768,0.005230169,0.01641403],"study_design_scores_gemma":[0.00004209006,0.0002522975,0.9958068,0.00005197968,0.0001888678,0.000230902,0.0004949048,0.0007534164,0.00006776772,0.0004131296,0.001670511,0.0000273429],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846143,0.001140045,0.0001953984,0.0005540977,0.00006775309,0.00001177856,0.01131618,0.00003337878,0.002067265],"genre_scores_gemma":[0.9881621,0.0003653632,0.000121835,0.00005943053,0.00005032085,0.000008003283,0.01023875,0.00002290189,0.0009713512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01576467,"threshold_uncertainty_score":0.03134578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09482295586577066,"score_gpt":0.4648350956021621,"score_spread":0.3700121397363915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}