{"id":"W4413791664","doi":"10.1016/s2152-2650(25)01097-3","title":"POSTER: ABCL-1487 Large B-Cell Lymphoma Microenvironment Archetype Profiles (LymphoMAPs) Clinically Identify Subgroups With Greatest Benefit From CD19 CAR T-Cell Therapy","year":2025,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Spinal Cord Injury BC","funders":"","keywords":"Medicine; CD19; Lymphoma; CAR T-cell therapy; Internal medicine; Oncology; Immunology; Immunotherapy; Chimeric antigen receptor; Cancer; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005365676,0.0005584427,0.0003562433,0.0004657748,0.0005670037,0.001102206,0.0002715556,0.0009902017,0.09352336],"category_scores_gemma":[0.0005790758,0.0001376242,0.0003617675,0.0001914319,0.0003214237,0.0004016364,0.000470752,0.001148117,0.02413431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005730691,"about_ca_system_score_gemma":0.00050978,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003800374,"about_ca_topic_score_gemma":0.001102883,"domain_scores_codex":[0.9998266,0.00003802144,0.000008921448,0.00003184095,0.00003489815,0.00005970111],"domain_scores_gemma":[0.9996474,0.00005981857,0.00002733756,0.00001472052,0.00005850201,0.0001922212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.01171243,0.00114366,0.01739603,0.0005947181,0.0001897341,0.001244994,0.0001000574,0.0003765637,0.02915887,0.002282373,0.56243,0.3733706],"study_design_scores_gemma":[0.007547096,0.008671314,0.09921122,0.0005024172,0.0005683246,0.008254183,0.0004988452,0.002081087,0.03579895,0.005798652,0.8309785,0.00008945423],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.4082452,0.02656033,0.004758682,0.09846321,0.02191078,0.002487512,0.01181646,0.002343169,0.4234146],"genre_scores_gemma":[0.6391971,0.007449698,0.004657545,0.01848865,0.01239925,0.0007596398,0.007264253,0.000294266,0.3094896],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.09352336,"threshold_uncertainty_score":0.3128668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02449232846229706,"score_gpt":0.3206075723707601,"score_spread":0.2961152439084631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}