{"id":"W4413792434","doi":"10.1101/2025.08.26.25334500","title":"Progenitor Cells, Regenerative Capacity, and Cognition","year":2025,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Progenitor cell; Cognition; Regenerative medicine; Progenitor; Regeneration (biology); Neuroscience; Cognitive science; Stem cell; Psychology; Cell biology; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005593405,0.0002871337,0.0002924033,0.0006750453,0.0001534285,0.0004453492,0.000297369,0.0002111625,0.00155549],"category_scores_gemma":[0.001652083,0.0001021764,0.0001607443,0.0006548629,0.0002438107,0.0001354887,0.0002745573,0.000374333,0.000138548],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001679966,"about_ca_system_score_gemma":0.00027591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003625812,"about_ca_topic_score_gemma":0.002418835,"domain_scores_codex":[0.9998506,0.00004154702,0.00001140334,0.00003723444,0.00003416043,0.00002486381],"domain_scores_gemma":[0.9990907,0.0002458697,0.0003219517,0.00005945202,0.0001491157,0.0001329219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009982968,0.0001789555,0.9709028,0.0001387364,0.0003600273,0.0001637268,0.000236959,0.0008575416,0.006338871,0.000233902,0.0004114153,0.01917877],"study_design_scores_gemma":[0.00002217609,0.0003415506,0.9950455,0.00003182134,0.0001013077,0.0002546417,0.0001481258,0.0009950445,0.001558539,0.0007289436,0.0007629535,0.000009393765],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974846,0.00117287,0.0002450113,0.00006055786,0.00000543727,0.000008986061,0.0006281865,0.000008448897,0.0003859645],"genre_scores_gemma":[0.9988381,0.0002745389,0.0002874288,0.00002697309,0.00001248422,0.00001385881,0.0003385036,0.000001294081,0.0002067981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003625812,"threshold_uncertainty_score":0.00720942,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02437868979414824,"score_gpt":0.244551377149524,"score_spread":0.2201726873553758,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}