{"id":"W4413796114","doi":"10.1016/j.annonc.2025.08.003","title":"Early and locally advanced non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up","year":2025,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Lung Cancer Diagnosis and Treatment","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Foundation Medicine; Chugai Pharmaceutical; Genentech; Nordic Pharma Group; Sociedad Española de Oncología Médica; PharmaMar; European Society for Medical Oncology; Eisai; Array BioPharma; European School of Oncology; Sanofi; Apollomics; Teva Pharmaceutical Industries; Les Laboratories Pierre Fabre; AstraZeneca; Novocure; Regeneron Pharmaceuticals; International Association for the Study of Lung Cancer; BeiGene; F. Hoffmann-La Roche; Varian Medical Systems; Kasturba Medical College, Manipal; Pfizer; Incyte; Daiichi Sankyo Europe; Gilead Sciences; Roche; Novartis; GlaxoSmithKline; Amgen; Ignyta; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Guideline; Lung cancer; Clinical Practice; Cancer; Oncology; Intensive care medicine; Medical physics; Internal medicine; Family medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00445708,0.001062714,0.002002322,0.002804152,0.001090889,0.001346928,0.002762182,0.004376916,0.002816679],"category_scores_gemma":[0.01487523,0.0007778239,0.002883434,0.002273014,0.0005891364,0.001245992,0.002071922,0.00544796,0.002698787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003620367,"about_ca_system_score_gemma":0.009610849,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03411039,"about_ca_topic_score_gemma":0.09860993,"domain_scores_codex":[0.9958776,0.001042514,0.00130185,0.0002087111,0.001176178,0.0003931337],"domain_scores_gemma":[0.9894108,0.002031831,0.001779736,0.0002086574,0.005573375,0.0009956298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001307493,0.0002611344,0.02432092,0.002129106,0.000268929,0.0007069489,0.0002842859,0.001946925,0.00135154,0.002165856,0.8094593,0.1569743],"study_design_scores_gemma":[0.0003622707,0.0002742599,0.1054263,0.01756162,0.0009443999,0.004779927,0.0007065007,0.003856287,0.001341036,0.005658788,0.8589304,0.0001582435],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.02458943,0.2330586,0.05639549,0.4488609,0.01894061,0.007414912,0.04447081,0.002371645,0.1638976],"genre_scores_gemma":[0.1608251,0.2113255,0.302712,0.1302146,0.01185613,0.0157147,0.1020423,0.0008724841,0.06443741],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.03411039,"threshold_uncertainty_score":0.06782371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05507737742056936,"score_gpt":0.4663043260235319,"score_spread":0.4112269486029626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}