{"id":"W4413799555","doi":"10.1038/s41598-025-16885-7","title":"Horse model of spontaneous atrial fibrillation share proteomic changes with humans","year":2025,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Heart Institute","funders":"Canadian Institutes of Health Research; Novo Nordisk Fonden; Lundbeckfonden","keywords":"Atrial fibrillation; Medicine; Horse; Internal medicine; Cardiology; Proteomics; Bioinformatics; Biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004857136,0.0004236268,0.0005364922,0.000824353,0.0006535166,0.0008614361,0.0002949504,0.000747114,0.002454334],"category_scores_gemma":[0.0008243741,0.0001966539,0.0005387538,0.0003369441,0.0006111926,0.0005642567,0.0005011492,0.0006312693,0.0005165135],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002616811,"about_ca_system_score_gemma":0.0002827909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001011825,"about_ca_topic_score_gemma":0.001506344,"domain_scores_codex":[0.9995881,0.00006552607,0.00003586012,0.0001601292,0.00009074042,0.00005972137],"domain_scores_gemma":[0.9995961,0.00006595851,0.0001206616,0.0000623957,0.00007442817,0.00008041513],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004688424,0.0006195389,0.09934816,0.0008662152,0.0005522356,0.003584452,0.000815742,0.0006753355,0.8475854,0.001258842,0.004627833,0.03537783],"study_design_scores_gemma":[0.0003326361,0.004938559,0.7631401,0.0003674888,0.000923381,0.0242089,0.001983714,0.007368599,0.1455019,0.004304691,0.04672496,0.0002052463],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806872,0.00238451,0.009490617,0.0006864464,0.0002362684,0.0001339939,0.004322719,0.0001899558,0.001868307],"genre_scores_gemma":[0.9819365,0.001277116,0.006726787,0.0006083817,0.00009449387,0.0003802917,0.006760222,0.00009182615,0.002124427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002454334,"threshold_uncertainty_score":0.008210599,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04337185572886608,"score_gpt":0.3063633492306873,"score_spread":0.2629914935018212,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}