{"id":"W4413831804","doi":"10.5334/gh.1457","title":"WHF Roadmap on Single Pill Combination Therapies","year":2025,"lang":"en","type":"review","venue":"Global Heart","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences; McMaster University; Population Health Research Institute","funders":"World Heart Federation","keywords":"Medicine; Pill; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006104982,0.0002743196,0.0009230509,0.00006779398,0.00006042728,0.00002164837,0.00006115962,0.0002096751,0.00007696879],"category_scores_gemma":[0.00002310897,0.0001982179,0.0003728659,0.0002644246,0.00002865901,0.00001961361,0.0000276097,0.0001536247,0.0004595989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000373073,"about_ca_system_score_gemma":0.0002253854,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005100301,"about_ca_topic_score_gemma":0.00002645754,"domain_scores_codex":[0.9989853,0.00007775203,0.0002361706,0.0002872322,0.0002155554,0.0001980098],"domain_scores_gemma":[0.9994485,0.00004545067,0.00005580649,0.0003325921,0.00004416732,0.00007343527],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001251596,0.0007341282,0.0002508633,0.004902877,0.0002047002,0.000004936235,0.000009074296,1.291941e-8,3.369403e-8,0.001370445,0.006070682,0.9864397],"study_design_scores_gemma":[0.0005073458,0.0005377502,0.000845005,0.00986288,0.0006841233,0.00004630657,0.000005275385,1.731164e-7,5.948809e-7,0.0002753438,0.9871109,0.0001243744],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000005802746,0.9565125,0.000004007949,0.000484212,0.0003535706,0.0008075688,0.00008994267,0.000082383,0.04166006],"genre_scores_gemma":[0.0002716215,0.9968277,0.0000671012,0.0002910499,0.00006934663,0.00005775511,0.0003452971,0.00001418289,0.002056006],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9863154,"threshold_uncertainty_score":0.8083091,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04099898008394721,"score_gpt":0.3625311230022921,"score_spread":0.3215321429183449,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}