{"id":"W4413832409","doi":"10.3390/vaccines13090921","title":"ImmuniT Platform for Improved Neoantigen Prediction in Lung Cancer","year":2025,"lang":"en","type":"article","venue":"Vaccines","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"National Center for Advancing Translational Sciences; National Cancer Institute; National Institutes of Health; U.S. Department of Defense","keywords":"Lung cancer; Cancer; Medicine; Computational biology; Computer science; Oncology; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001176803,0.00009164223,0.0001714784,0.0001695195,0.00005321191,0.00001139947,0.00005864388,0.00007369817,0.0001913277],"category_scores_gemma":[0.00002382778,0.00007462886,0.00007534781,0.000291616,0.000007843611,0.00007095518,0.00001492317,0.00007322495,0.000001031319],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000122916,"about_ca_system_score_gemma":0.0001368357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007975097,"about_ca_topic_score_gemma":0.0004443015,"domain_scores_codex":[0.9994427,0.00000474898,0.0002161769,0.0001375067,0.00003755466,0.0001613028],"domain_scores_gemma":[0.9996837,0.00003757644,0.0000382661,0.0001624927,0.0000586084,0.00001932646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.02034291,0.0002725247,0.2443841,0.001204333,0.000841836,0.000003302122,0.0006895622,0.00002001387,0.3322081,0.0002123262,0.05937241,0.3404486],"study_design_scores_gemma":[0.01767538,0.0003445064,0.7073575,0.0009599262,0.000242661,0.000007327385,0.0003194252,0.0163531,0.04026355,0.000248054,0.2159932,0.0002353617],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841931,0.008244972,0.0004381708,0.003438854,0.0008934597,0.001152187,0.00004625626,0.00007414062,0.001518845],"genre_scores_gemma":[0.9810615,0.001769611,0.0002828339,0.001329006,0.0002690797,0.0004494441,0.00007980064,0.00002217207,0.01473659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4629734,"threshold_uncertainty_score":0.3043277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01374189330591971,"score_gpt":0.3089914094098673,"score_spread":0.2952495161039476,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}