{"id":"W4413832409","doi":"10.3390/vaccines13090921","title":"ImmuniT Platform for Improved Neoantigen Prediction in Lung Cancer","year":2025,"lang":"en","type":"article","venue":"Vaccines","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"National Center for Advancing Translational Sciences; National Cancer Institute; National Institutes of Health; U.S. Department of Defense","keywords":"Lung cancer; Cancer; Medicine; Computational biology; Computer science; Oncology; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001281806,0.0007932754,0.0004742919,0.001013768,0.0002519896,0.0009017831,0.0005280297,0.0005897428,0.003169309],"category_scores_gemma":[0.001378797,0.00032305,0.0005143008,0.0002437043,0.0001934702,0.000580264,0.001020662,0.0008277525,0.00102319],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004680536,"about_ca_system_score_gemma":0.000545548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006129196,"about_ca_topic_score_gemma":0.001096005,"domain_scores_codex":[0.9996719,0.00005910186,0.00001915564,0.0001136207,0.00009268149,0.0000434437],"domain_scores_gemma":[0.9996118,0.0001457551,0.00007947065,0.00003413602,0.00008168557,0.00004718464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003149769,0.0006196894,0.04577955,0.0008118064,0.0003072027,0.0007245826,0.0002221871,0.02314295,0.7469684,0.002428597,0.01073674,0.1651084],"study_design_scores_gemma":[0.0002339008,0.002044837,0.02226659,0.000129355,0.0003491216,0.001764779,0.0001280945,0.4101502,0.531464,0.003902942,0.02744071,0.0001254254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.7450446,0.004839062,0.2225879,0.001039239,0.0002134483,0.0007271359,0.006893937,0.01055874,0.008096009],"genre_scores_gemma":[0.7884318,0.001098436,0.1954778,0.0009576512,0.0001038323,0.0004657666,0.009120942,0.0005073246,0.003836548],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.003169309,"threshold_uncertainty_score":0.01060236,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01374189330591971,"score_gpt":0.3089914094098673,"score_spread":0.2952495161039476,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}