{"id":"W4413840875","doi":"10.1093/jas/skaf298","title":"Serum metabolomics reveals one-carbon metabolism differences between lean and obese cats not affected by L-carnitine or choline supplementation","year":2025,"lang":"en","type":"article","venue":"Journal of Animal Science","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Balchem","keywords":"CATS; Choline; Carnitine; Internal medicine; Endocrinology; Overweight; Medicine; Analysis of variance; Lipid metabolism; Animal science; Chemistry; Body mass index; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001556705,0.0002015951,0.0003209527,0.0003815139,0.0001826757,0.0003012725,0.00008744486,0.0002830148,0.0008701879],"category_scores_gemma":[0.0002250847,0.0001501316,0.0001837397,0.0001858887,0.0002715605,0.000182106,0.0001941715,0.0003805965,0.0001147195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002395749,"about_ca_system_score_gemma":0.0002034386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002211987,"about_ca_topic_score_gemma":0.00502672,"domain_scores_codex":[0.9998925,0.00001313163,0.00001052752,0.00003704724,0.00002574723,0.00002113612],"domain_scores_gemma":[0.9998209,0.000017271,0.00005854532,0.00001319023,0.00002942376,0.00006077674],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.005803382,0.0002026246,0.02627237,0.00007823572,0.00005948982,0.0001560953,0.0001322087,0.00004254105,0.9628778,0.0000315414,0.00006922,0.004274574],"study_design_scores_gemma":[0.00009142414,0.006089804,0.8419425,0.00002152604,0.0001876984,0.0005434166,0.000481643,0.0008380392,0.1484775,0.00005745798,0.001250131,0.00001883902],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993938,0.0001735475,0.00009825708,0.00001883643,0.000003503773,0.00000802878,0.0001695955,0.000003780931,0.000130741],"genre_scores_gemma":[0.9973544,0.0002282459,0.0006262022,0.00008829271,0.000002501871,0.00003037381,0.0005535992,0.000004156986,0.001112227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002211987,"threshold_uncertainty_score":0.004398227,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0192182628315329,"score_gpt":0.3007062935420902,"score_spread":0.2814880307105573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}