{"id":"W4413848365","doi":"10.1016/j.fct.2025.115719","title":"Decoding premature ovarian insufficiency: A full spectrum review from epidemiology to management with emphasis on cyclophosphamide-evoked ovarian injury","year":2025,"lang":"en","type":"review","venue":"Food and Chemical Toxicology","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Canadian Physiotherapy Association","keywords":"Premature ovarian failure; Premature ovarian insufficiency; Cyclophosphamide; Epidemiology; Medicine; Internal medicine; Chemotherapy","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007235942,0.0009406561,0.002341934,0.002931028,0.0002251148,0.001155499,0.0008659607,0.001118548,0.003675775],"category_scores_gemma":[0.001861115,0.0003486962,0.0009904244,0.002240817,0.0003680727,0.00141668,0.0008858526,0.001488778,0.0009746649],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004927149,"about_ca_system_score_gemma":0.001465878,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001335197,"about_ca_topic_score_gemma":0.003346738,"domain_scores_codex":[0.9996889,0.00006939939,0.00008136779,0.00005521553,0.00008300025,0.00002214718],"domain_scores_gemma":[0.9990171,0.0006458097,0.0001218054,0.00001588866,0.0001561658,0.00004326183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001387869,0.00008073648,0.0004220783,0.06957472,0.0004500271,0.0003923576,0.00005702901,0.0003235293,0.0008165442,0.00112081,0.03496424,0.8916591],"study_design_scores_gemma":[0.0001472391,0.0003521591,0.003221859,0.05710975,0.001842773,0.004690156,0.0001717352,0.0002886405,0.0004972026,0.001925207,0.929671,0.00008221155],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003862661,0.9994895,0.00005638483,0.00010935,0.0001218666,0.000004186101,0.00001517333,0.000002744862,0.0001620635],"genre_scores_gemma":[0.0002787591,0.9990888,0.0001411633,0.0002136994,0.0001485046,0.000004252418,0.00002839852,8.432374e-7,0.00009568493],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003675775,"threshold_uncertainty_score":0.01229674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03467024303071393,"score_gpt":0.3388515489412879,"score_spread":0.304181305910574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}