{"id":"W4413848379","doi":"10.1016/j.pneurobio.2025.102821","title":"Rodent models of Alzheimer's disease: Critical analysis of current hypotheses and pathways for future research","year":2025,"lang":"en","type":"review","venue":"Progress in Neurobiology","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Australian Research Council; Medical Research Council; Bundesministerium für Bildung und Forschung; Agence Nationale de la Recherche; RMIT University; Australian Government; National Health and Medical Research Council; European Commission; Canadian Institutes of Health Research; EU Joint Programme – Neurodegenerative Disease Research","keywords":"Neuroscience; Disease; Current (fluid); Alzheimer's disease; Rodent model; Psychology; Brain research; Biology; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005304609,0.0003683774,0.002768771,0.001814764,0.00005889334,0.00001192228,0.0002675251,0.0002578321,0.00001636756],"category_scores_gemma":[0.0004573959,0.0002641101,0.0007635613,0.001307404,0.0009903525,0.0000422868,0.000327875,0.0005199645,8.858897e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004828897,"about_ca_system_score_gemma":0.001055573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004516132,"about_ca_topic_score_gemma":0.000004083511,"domain_scores_codex":[0.9965119,0.0008383983,0.0008511761,0.0008114269,0.0003580899,0.0006289756],"domain_scores_gemma":[0.996432,0.001912055,0.0001958655,0.0006373294,0.0004812842,0.0003414848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0005842624,0.002222857,0.0053103,0.05171252,0.02091719,0.0001034178,0.00003599679,0.000001747042,1.410045e-7,0.007554348,0.00006569613,0.9114915],"study_design_scores_gemma":[0.01171365,0.01087503,0.03301362,0.1687479,0.5611877,0.00009084498,0.000299775,0.00343008,0.0000834138,0.02310781,0.1841882,0.003261996],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003111309,0.9947047,0.000008336157,0.00009128837,0.0001304605,0.002663987,0.002044913,0.0000148474,0.00003038835],"genre_scores_gemma":[0.02012231,0.9773992,0.000116025,0.000005792911,0.0000846262,0.001499861,0.0007377064,0.00003221742,0.000002216212],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9082295,"threshold_uncertainty_score":0.9999811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2403240573361554,"score_gpt":0.4947567332906875,"score_spread":0.2544326759545321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}