{"id":"W4413849555","doi":"10.1161/circulationaha.125.076704","title":"Ivabradine in Patients Undergoing Noncardiac Surgery: A Randomized Controlled Trial","year":2025,"lang":"en","type":"article","venue":"Circulation","topic":"Heart rate and cardiovascular health","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Population Health Research Institute","funders":"Agencja Badań Medycznych","keywords":"Medicine; Ivabradine; Placebo; Anesthesia; Perioperative; Myocardial infarction; Stroke (engine); Randomization; Heart rate; Randomized controlled trial; Confidence interval; Clinical endpoint; Interim analysis; Cardiology; Internal medicine; Surgery; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002537728,0.001136059,0.003557313,0.0004945212,0.0003763235,0.001308343,0.0007518789,0.001844858,0.007397291],"category_scores_gemma":[0.003853269,0.0005367422,0.002167713,0.0006909005,0.0008127379,0.0007408752,0.0003385911,0.001852571,0.0005846619],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006003607,"about_ca_system_score_gemma":0.001048748,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007878374,"about_ca_topic_score_gemma":0.001404203,"domain_scores_codex":[0.9986571,0.0007800899,0.0001525498,0.0002106927,0.00009278124,0.0001068],"domain_scores_gemma":[0.99845,0.000562199,0.0005373604,0.00009646476,0.0001106173,0.0002433278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9714198,0.002001097,0.0007645854,0.005800141,0.003157912,0.00004786716,0.00003977928,0.0001793307,0.001001012,0.0001382699,0.001024125,0.01442608],"study_design_scores_gemma":[0.9902676,0.007115738,0.0007621455,0.00018512,0.0009483042,0.00001410541,0.00001177098,0.0001198032,0.00006103503,0.00008424464,0.000424086,0.000006140714],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8472458,0.1274026,0.001744415,0.003875072,0.004101535,0.008167533,0.002158379,0.000239448,0.005065287],"genre_scores_gemma":[0.9462073,0.0345663,0.002321318,0.002829486,0.001832782,0.008671639,0.001143909,0.00002630506,0.002400864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007397291,"threshold_uncertainty_score":0.02474642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01187788212264515,"score_gpt":0.2727868392385829,"score_spread":0.2609089571159378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}