{"id":"W4413855545","doi":"10.1016/j.jacc.2025.08.046","title":"Sex Differences in Effectiveness of Semaglutide in Patients With Peripheral Artery Disease","year":2025,"lang":"en","type":"article","venue":"Journal of the American College of Cardiology","topic":"Peripheral Artery Disease Management","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital","funders":"Novo Nordisk","keywords":"Medicine; Semaglutide; STRIDE; Peripheral; Arterial disease; Internal medicine; Physical therapy; Cardiology; Physical medicine and rehabilitation; Diabetes mellitus; Endocrinology; Type 2 diabetes; Vascular disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003338876,0.0001192832,0.001031904,0.000256664,0.00001360108,0.00000158781,0.0001931139,0.00001819378,0.000003519394],"category_scores_gemma":[0.000107359,0.000070507,0.0001902103,0.0005065323,0.0003861198,0.00003403306,0.0000753599,0.0001521849,9.908148e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000158878,"about_ca_system_score_gemma":0.0002415707,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001491362,"about_ca_topic_score_gemma":0.000008147059,"domain_scores_codex":[0.9984248,0.0006142248,0.0004435315,0.0001226843,0.0002381442,0.0001566414],"domain_scores_gemma":[0.999036,0.0001629516,0.0003723281,0.0002383655,0.0001274313,0.00006298748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00730858,0.000205383,0.9900507,0.0001811301,0.000312826,0.0001318058,0.00002099166,0.000922257,0.0002290448,0.00003554135,0.0001096345,0.0004920516],"study_design_scores_gemma":[0.003226199,0.0008751294,0.9945296,0.0006137431,0.0001603234,0.000009718669,0.0002089417,0.0000590042,0.00004692172,0.0001601837,0.00005262887,0.00005757892],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984959,0.00009292831,0.00007861498,0.0004645861,0.000113018,0.0003650414,0.00002777998,0.000001977128,0.0003600919],"genre_scores_gemma":[0.9996646,0.00001291782,0.00006998492,0.0001534731,0.00002402419,0.000009079999,7.666293e-7,0.000006234246,0.00005894294],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004478873,"threshold_uncertainty_score":0.2875192,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005193703335694926,"score_gpt":0.2338317152541962,"score_spread":0.2286380119185012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}