{"id":"W4413855545","doi":"10.1016/j.jacc.2025.08.046","title":"Sex Differences in Effectiveness of Semaglutide in Patients With Peripheral Artery Disease","year":2025,"lang":"en","type":"article","venue":"Journal of the American College of Cardiology","topic":"Peripheral Artery Disease Management","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital","funders":"Novo Nordisk","keywords":"Medicine; Semaglutide; STRIDE; Peripheral; Arterial disease; Internal medicine; Physical therapy; Cardiology; Physical medicine and rehabilitation; Diabetes mellitus; Endocrinology; Type 2 diabetes; Vascular disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005297367,0.0001759317,0.0006389043,0.0003474361,0.0001671783,0.0006554033,0.0001700406,0.0004080513,0.002272234],"category_scores_gemma":[0.003475495,0.000142345,0.00074077,0.0004049279,0.0001745482,0.0004357309,0.0002113089,0.0005573465,0.0002541978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002996098,"about_ca_system_score_gemma":0.0002588128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008873347,"about_ca_topic_score_gemma":0.001375669,"domain_scores_codex":[0.9996046,0.0001012318,0.00005754803,0.00006399897,0.00008127037,0.00009137969],"domain_scores_gemma":[0.9981918,0.0007857223,0.0005407259,0.0001066461,0.0001067497,0.0002684364],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008813874,0.0002499464,0.9700471,0.00005353206,0.0009942211,0.0004618461,0.0001323099,0.0001670378,0.001631095,0.0001690042,0.0003093561,0.01697073],"study_design_scores_gemma":[0.0001281543,0.0006372541,0.9981151,0.0000113818,0.0001664838,0.0003217229,0.0001014032,0.0001434237,0.00009449637,0.00006139802,0.0002133786,0.00000592343],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951309,0.002247775,0.00006088276,0.0001627012,0.00003722992,0.000005294884,0.0001879839,0.000003574544,0.002163619],"genre_scores_gemma":[0.9991596,0.0003070143,0.00002194629,0.000104257,0.0000452032,0.000003051607,0.0001179758,0.000003132034,0.0002377521],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002272234,"threshold_uncertainty_score":0.00760144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005193703335694926,"score_gpt":0.2338317152541962,"score_spread":0.2286380119185012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}