{"id":"W4413861608","doi":"10.7759/cureus.91343","title":"A Retrospective Crossover Study on Cross-Linked Hyaluronic Acid Gel (Lacrifill) Versus Cyclosporine A 0.05% (Restasis) for Dry Eye Disease","year":2025,"lang":"en","type":"article","venue":"Cureus","topic":"Ocular Surface and Contact Lens","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Columbia College","funders":"","keywords":"Medicine; Hyaluronic acid; Disease; Crossover study; Ophthalmology; Retrospective cohort study; Dry eyes; Internal medicine; Pathology; Anatomy; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002952839,0.0008827018,0.002621724,0.0004972085,0.0005846407,0.0006610684,0.0005023503,0.0008275282,0.002642711],"category_scores_gemma":[0.003006383,0.0003836186,0.001481442,0.0004843571,0.0009970332,0.0008081078,0.0003251834,0.001074228,0.0004949108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003900582,"about_ca_system_score_gemma":0.000549136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004082474,"about_ca_topic_score_gemma":0.0005588127,"domain_scores_codex":[0.9985434,0.000695398,0.0001637398,0.0003006989,0.0001447628,0.0001520168],"domain_scores_gemma":[0.9977484,0.0007729264,0.0005590445,0.0003066147,0.0001638214,0.0004492311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8720276,0.04946775,0.01926048,0.0007619298,0.001440844,0.0004370234,0.0005092464,0.0003866291,0.02421445,0.0001265425,0.0003910188,0.03097653],"study_design_scores_gemma":[0.1442751,0.8223227,0.02959808,0.00002914151,0.0006618541,0.0002337986,0.0001303205,0.0002633687,0.001672197,0.00005748286,0.0007310694,0.0000249437],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978864,0.0008173533,0.0002847537,0.00003377575,0.00008631266,0.0005521122,0.0001251152,0.0000123963,0.0002017553],"genre_scores_gemma":[0.9975166,0.0004513449,0.0006308262,0.0001343296,0.0002103923,0.0004253548,0.0002575175,0.000007529329,0.0003659595],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002952839,"threshold_uncertainty_score":0.0156163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02354313179254139,"score_gpt":0.355656853038902,"score_spread":0.3321137212463606,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}