{"id":"W4413874897","doi":"10.3390/medicina61091569","title":"Proton Pump Inhibitors (PPIs)—An Evidence-Based Review of Indications, Efficacy, Harms, and Deprescribing","year":2025,"lang":"en","type":"review","venue":"Medicina","topic":"Gastroesophageal reflux and treatments","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Deprescribing; Intensive care medicine; Medicine; Polypharmacy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000873483,0.0005114233,0.002646148,0.0004723689,0.00007975534,0.00001236155,0.0002315614,0.0002608606,0.0001154591],"category_scores_gemma":[0.00222929,0.0003413283,0.0003246934,0.0006255168,0.0001867395,0.0001065706,0.00008636311,0.0005145766,0.00002146759],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001748113,"about_ca_system_score_gemma":0.001417476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003147562,"about_ca_topic_score_gemma":6.469368e-7,"domain_scores_codex":[0.99686,0.0003362758,0.001143566,0.0006605937,0.0006812948,0.0003182449],"domain_scores_gemma":[0.9974025,0.0005562269,0.000657751,0.0008862421,0.0001494398,0.0003478233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.000009965438,0.0002099266,0.0008678267,0.3739053,0.0001610157,0.0001177422,0.00001854847,9.941412e-9,4.102995e-7,0.000006861473,0.0004487335,0.6242536],"study_design_scores_gemma":[0.001026384,0.0007019711,0.0005069746,0.8254038,0.007403955,0.00006271853,0.000005447929,0.000001107114,0.00004824078,0.000003876721,0.1647073,0.0001282595],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007238637,0.9920155,0.00002086628,0.0002892875,0.0001603095,0.006977261,0.00003456793,0.00006184634,0.000367927],"genre_scores_gemma":[0.001012415,0.9964823,0.0003090553,0.0005258847,0.0001689601,0.0006310711,0.0005745889,0.00004526761,0.0002504913],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6241254,"threshold_uncertainty_score":0.9999039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08439919160084196,"score_gpt":0.4025488374735308,"score_spread":0.3181496458726888,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}