{"id":"W4413894456","doi":"10.1038/s41598-025-15721-2","title":"Uncovering novel functions of NUF2 in glioblastoma and MRI-based expression prediction","year":2025,"lang":"en","type":"article","venue":"Scientific Reports","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Sanming Project of Medicine in Shenzhen","keywords":"Glioblastoma; Computational biology; Computer science; Expression (computer science); Bioinformatics; Biology; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005091386,0.0006750955,0.000583549,0.001022469,0.0001815138,0.000533066,0.00028861,0.0004620939,0.0003978257],"category_scores_gemma":[0.0006998042,0.0001505493,0.0006376393,0.0004056177,0.0001626326,0.0002802617,0.0002408696,0.0002963465,0.0002260679],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003599764,"about_ca_system_score_gemma":0.0004306302,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003394461,"about_ca_topic_score_gemma":0.002941577,"domain_scores_codex":[0.9998868,0.00002518529,0.00000701649,0.00003625112,0.00002132293,0.00002347001],"domain_scores_gemma":[0.9998928,0.00003683131,0.00002453228,0.000008717904,0.000023776,0.00001336726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001210584,0.0006124722,0.2857321,0.0002652783,0.0004326671,0.001021444,0.0001375359,0.2518119,0.1115779,0.001090167,0.003284441,0.3428237],"study_design_scores_gemma":[0.00001716794,0.00014772,0.04249898,0.00001790105,0.00008123777,0.0003382997,0.00004079678,0.9459937,0.009042806,0.0008820278,0.0009139128,0.00002552447],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9082147,0.002489659,0.08631589,0.0002931881,0.00002248297,0.00006817324,0.0007964117,0.0007879714,0.001011527],"genre_scores_gemma":[0.9848551,0.0004156888,0.01306579,0.00003926122,0.00001654254,0.00004534156,0.001029941,0.00001659925,0.0005156728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003394461,"threshold_uncertainty_score":0.006749392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006428279150526984,"score_gpt":0.2366512534606063,"score_spread":0.2302229743100793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}