{"id":"W4413898585","doi":"10.26599/1671-5411.2025.07.004","title":"Study design and rationale of the TXL-CAP trial: a randomized, double-blind, placebo-controlled, multicenter clinical trial assessing the effect of Tongxinluo capsules on the stability of coronary atherosclerotic plaques","year":2025,"lang":"en","type":"article","venue":"Journal of Geriatric Cardiology","topic":"Lipid metabolism and disorders","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Placebo; Clinical trial; Randomized controlled trial; Double blind; Internal medicine; Cardiology; Pathology; Alternative medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02244461,0.004708533,0.007929523,0.001495004,0.002462495,0.002337182,0.002902902,0.005223794,0.01015651],"category_scores_gemma":[0.01397672,0.002246431,0.002356849,0.001892116,0.004514509,0.002143709,0.001362392,0.005792725,0.003849689],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001095894,"about_ca_system_score_gemma":0.006926029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005670543,"about_ca_topic_score_gemma":0.001005728,"domain_scores_codex":[0.9862996,0.008673271,0.001047895,0.00173511,0.001371823,0.0008723719],"domain_scores_gemma":[0.9962196,0.001056867,0.0006243598,0.0004556584,0.0006382426,0.001005401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8533794,0.02252712,0.005545419,0.01937027,0.002616778,0.000728145,0.0005547378,0.00188847,0.009777601,0.01237606,0.01222975,0.05900617],"study_design_scores_gemma":[0.8733502,0.07631465,0.004072397,0.001589211,0.002503522,0.0002509616,0.0001587722,0.002247572,0.001603523,0.005366126,0.03236229,0.0001808404],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"methods","genre_scores_codex":[0.03642913,0.01097219,0.01388177,0.003266119,0.00409568,0.9228007,0.003241544,0.000349549,0.004963381],"genre_scores_gemma":[0.0437697,0.002881808,0.01918223,0.004261265,0.001157583,0.9261121,0.0009586026,0.0000279231,0.00164874],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.02244461,"threshold_uncertainty_score":0.1186998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06727387595716779,"score_gpt":0.3755488773339568,"score_spread":0.308275001376789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}