{"id":"W4413898585","doi":"10.26599/1671-5411.2025.07.004","title":"Study design and rationale of the TXL-CAP trial: a randomized, double-blind, placebo-controlled, multicenter clinical trial assessing the effect of Tongxinluo capsules on the stability of coronary atherosclerotic plaques","year":2025,"lang":"en","type":"article","venue":"Journal of Geriatric Cardiology","topic":"Lipid metabolism and disorders","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Placebo; Clinical trial; Randomized controlled trial; Double blind; Internal medicine; Cardiology; Pathology; Alternative medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02012158,0.0002078733,0.002867051,0.0001452927,0.0000964353,0.00001715339,0.000272567,0.0001616746,0.00001535712],"category_scores_gemma":[0.007968133,0.00008001293,0.001244361,0.000226144,0.0006387707,0.00006355745,0.00009054449,0.0004636109,2.371083e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002952791,"about_ca_system_score_gemma":0.0004674529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002428119,"about_ca_topic_score_gemma":0.000002367527,"domain_scores_codex":[0.9869295,0.01011824,0.002153951,0.000203044,0.0004315512,0.0001637449],"domain_scores_gemma":[0.9766039,0.02087469,0.001733606,0.000410489,0.0003297867,0.00004757502],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9820845,0.0005037735,0.01349608,0.00005967607,0.002086546,0.000002446625,0.0004054526,0.0001973304,0.0003978426,0.00005862142,0.0002037545,0.0005040172],"study_design_scores_gemma":[0.9735934,0.004010302,0.01592344,0.00006690272,0.004405225,0.00001809522,0.001236351,0.0001145895,0.000447678,0.0001093734,0.00001859346,0.00005612111],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831451,0.001801814,0.0005504306,0.000679056,0.001935228,0.01171524,0.000004247494,0.000003585416,0.0001653385],"genre_scores_gemma":[0.9987921,0.000304882,0.00007833297,0.00006778629,0.0005960601,0.0001296144,6.408383e-7,0.00001035782,0.00002025512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01564701,"threshold_uncertainty_score":0.9539176,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06727387595716779,"score_gpt":0.3755488773339568,"score_spread":0.308275001376789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}