{"id":"W4413901804","doi":"10.1186/s13223-025-00985-0","title":"Duo biologic therapy using mepolizumab and omalizumab in refractory ABPA: two cases","year":2025,"lang":"en","type":"article","venue":"Allergy Asthma and Clinical Immunology","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Mepolizumab; Omalizumab; Medicine; Exacerbation; Allergic bronchopulmonary aspergillosis; Adverse effect; Refractory (planetary science); Concomitant; Dupilumab; Intensive care medicine; Benralizumab; Asthma; Internal medicine; Immunology; Dermatology; Eosinophil; Antibody; Immunoglobulin E","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000613721,0.002365898,0.001305979,0.002436908,0.003210237,0.001619261,0.00127123,0.00711546,0.001729524],"category_scores_gemma":[0.003687382,0.001063912,0.001713949,0.001191816,0.00206489,0.002000228,0.001972684,0.003984041,0.0007883233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001268958,"about_ca_system_score_gemma":0.0008069355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001983194,"about_ca_topic_score_gemma":0.002234795,"domain_scores_codex":[0.9987699,0.0001915265,0.0001537002,0.0002199315,0.0002146533,0.0004502192],"domain_scores_gemma":[0.9981328,0.0004800021,0.0004342901,0.0001424739,0.00008442032,0.0007261351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00002680816,0.00007128323,0.003520398,0.00002877415,0.00001047334,0.993766,0.0001779727,0.00004841703,0.000347248,0.0001963134,0.0002136127,0.001592745],"study_design_scores_gemma":[0.00001015112,0.00004322147,0.001735847,0.0000135053,0.000009125877,0.9970464,0.00008024069,0.0001344595,0.0001911033,0.00009439366,0.000633479,0.000008144669],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9508188,0.01624515,0.008568029,0.005362383,0.0009412522,0.0003710916,0.0001725932,0.0002000784,0.01732054],"genre_scores_gemma":[0.9903669,0.002420183,0.002167471,0.001681707,0.001242637,0.00006405744,0.00008900894,0.00003275121,0.001935265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00711546,"threshold_uncertainty_score":0.009206951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05225185464108357,"score_gpt":0.3943757425971287,"score_spread":0.3421238879560451,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}