{"id":"W4413904064","doi":"10.1016/j.humpath.2025.105926","title":"Assessment of Nectin4-expression in vulvar squamous cell carcinomas (VSCC): correlation with HPV-associated and HPV-independent molecular subtypes","year":2025,"lang":"en","type":"article","venue":"Human Pathology","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"","keywords":"Pathology; Correlation; Vulvar intraepithelial neoplasia; Medicine; Cancer research; Vulva","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002534024,0.0001540506,0.0002147773,0.0001148649,0.00006909355,0.000009987902,0.0001128293,0.0002296314,0.00003488701],"category_scores_gemma":[0.00002311417,0.0001429665,0.00003246132,0.0001147879,0.00008651758,0.000004126929,0.0001057214,0.0001449741,6.085422e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004160563,"about_ca_system_score_gemma":0.0001198423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002631585,"about_ca_topic_score_gemma":0.0001293425,"domain_scores_codex":[0.998907,0.0001399552,0.0002604618,0.0003739996,0.0001169929,0.0002015946],"domain_scores_gemma":[0.9995192,0.00001928966,0.0001490849,0.0001961859,0.00008663535,0.00002954907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00004961734,0.0000968364,0.307702,0.00003134561,0.00001281076,0.00003363259,0.00009969551,0.0003364777,0.6912596,0.0001508761,0.0001021553,0.0001249521],"study_design_scores_gemma":[0.001641475,0.0003817305,0.6367565,0.00002769683,0.0000305638,0.000007601623,0.00009358202,0.00006400694,0.3605568,0.000173192,0.000103351,0.0001634579],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921054,0.0007487026,0.001952729,0.00002042957,0.00009147149,0.0002026862,0.000004121379,0.00001062653,0.004863862],"genre_scores_gemma":[0.9984848,0.00002642466,0.0005300848,0.00007995024,0.00001398323,0.00003541116,0.0001197353,0.00001545873,0.000694106],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3307028,"threshold_uncertainty_score":0.5830005,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006221125321251728,"score_gpt":0.250059209141917,"score_spread":0.2438380838206653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}