{"id":"W4413910361","doi":"10.1128/spectrum.00274-25","title":"The avermectin, emamectin benzoate, kills gram-positive bacteria and targets the cell envelope of <i>Bacillus subtilis</i>","year":2025,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Agriculture and Agri-Food Canada","funders":"Government of Canada","keywords":"Biology; Emamectin; Bacillus subtilis; Avermectin; Microbiology; Peptidoglycan; Biochemistry; Bacteria; Emamectin benzoate; Cell wall; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004479493,0.0003602974,0.0005149459,0.00009832769,0.001015311,0.00004843228,0.0004981959,0.0004899556,0.0001998831],"category_scores_gemma":[0.00006694085,0.0002164607,0.0001702278,0.0002253754,0.001930261,0.00007437577,0.0004060492,0.0007608636,0.00009430953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004898099,"about_ca_system_score_gemma":0.0001104272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003897866,"about_ca_topic_score_gemma":0.0004212022,"domain_scores_codex":[0.9978708,0.0004407517,0.0004890073,0.0004860889,0.00001683387,0.000696506],"domain_scores_gemma":[0.998381,0.0007910843,0.0002802568,0.0004511707,0.00007730067,0.00001919135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002659121,0.00008292875,0.001193312,0.00002394469,0.0002852141,0.000003108938,0.0005106097,0.00000130535,0.9699575,0.001953603,0.02493329,0.000789281],"study_design_scores_gemma":[0.0007957503,0.0001807317,0.005165438,0.00004127749,0.00008063788,0.00013523,0.0007490389,6.616144e-7,0.8700315,0.0006189335,0.1219739,0.0002268998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788223,0.007811473,0.0001068445,0.005050106,0.002008253,0.0006423352,0.0003454562,0.00007045439,0.005142791],"genre_scores_gemma":[0.984073,0.0009135283,0.00005341567,0.0009925497,0.0000383412,0.00001794259,0.0001247777,0.00002098625,0.01376548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09992596,"threshold_uncertainty_score":0.8827009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003133288098367611,"score_gpt":0.1875184444875144,"score_spread":0.1843851563891468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}