{"id":"W4413910361","doi":"10.1128/spectrum.00274-25","title":"The avermectin, emamectin benzoate, kills gram-positive bacteria and targets the cell envelope of <i>Bacillus subtilis</i>","year":2025,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Agriculture and Agri-Food Canada","funders":"Government of Canada","keywords":"Biology; Emamectin; Bacillus subtilis; Avermectin; Microbiology; Peptidoglycan; Biochemistry; Bacteria; Emamectin benzoate; Cell wall; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000087221,0.0003155238,0.0001775999,0.0001569205,0.0001014548,0.0001916293,0.00009944854,0.0001963312,0.0009912467],"category_scores_gemma":[0.00008939391,0.00007589231,0.0001782249,0.00009148126,0.0001187215,0.0001306457,0.000179132,0.000318278,0.0002517358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001487746,"about_ca_system_score_gemma":0.0001017486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003732231,"about_ca_topic_score_gemma":0.0006654749,"domain_scores_codex":[0.9999064,0.00002086977,0.000007159579,0.00001830567,0.00002938082,0.00001791215],"domain_scores_gemma":[0.9999524,0.00000768351,0.00001869254,0.000004066246,0.000008419073,0.000008620336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000288086,0.000008825505,0.0001684115,0.00001811869,0.000002576626,0.00001039855,0.000001597615,0.00002541839,0.9989728,0.0000135717,0.000009213088,0.000740231],"study_design_scores_gemma":[0.000005389725,0.0003199861,0.005725079,0.000004751274,0.00000991411,0.0001144973,0.000008829186,0.0002243618,0.9919413,0.0000147605,0.001628961,0.000002017126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910955,0.002556719,0.003327642,0.0001087514,0.00002186767,0.00003791415,0.000440183,0.00007528676,0.00233599],"genre_scores_gemma":[0.9933522,0.0009698123,0.002791392,0.0001081078,0.000007593039,0.00002042418,0.0005420516,0.00001476078,0.002193663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009912467,"threshold_uncertainty_score":0.003316104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003133288098367611,"score_gpt":0.1875184444875144,"score_spread":0.1843851563891468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}