{"id":"W4413910371","doi":"10.1093/ecco-jcc/jjaf159","title":"Fecal loss of vedolizumab is associated with ulcerative colitis severity, lower serum vedolizumab levels, and rates of clinical response: results from the FAVOUR study","year":2025,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Thomas Hospital","funders":"","keywords":"Vedolizumab; Medicine; Internal medicine; Gastroenterology; Area under the curve; Ulcerative colitis; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002983337,0.0003055604,0.0006718449,0.0006612993,0.0002295487,0.0007764262,0.000299485,0.0004340837,0.002097225],"category_scores_gemma":[0.007081412,0.0002738177,0.0006662091,0.0004898672,0.0003741356,0.000458862,0.0006377046,0.0004985095,0.0002527979],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002979553,"about_ca_system_score_gemma":0.0002202161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004141564,"about_ca_topic_score_gemma":0.0005915727,"domain_scores_codex":[0.9986664,0.0005241677,0.0002133806,0.0001491407,0.0003624689,0.00008449695],"domain_scores_gemma":[0.9914853,0.002908142,0.003716928,0.0005074598,0.0007250516,0.0006570792],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03781094,0.0004261047,0.9436663,0.0002900076,0.0004950055,0.00009107192,0.0001208836,0.0001145849,0.002921798,0.00002589749,0.00019135,0.01384607],"study_design_scores_gemma":[0.001822201,0.008114158,0.9856383,0.00005852346,0.0005674596,0.0008526933,0.0001681113,0.0004314243,0.001069538,0.00004753035,0.001209951,0.00002003507],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979943,0.001231825,0.00008603017,0.00004109344,0.000006563428,0.00002391645,0.0002206276,0.00000387519,0.0003917394],"genre_scores_gemma":[0.9990522,0.0002494915,0.0001294766,0.00002976144,0.00001920902,0.00001665998,0.0002962624,0.00000303479,0.0002038727],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002983337,"threshold_uncertainty_score":0.01577753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02102061499558739,"score_gpt":0.318885355110022,"score_spread":0.2978647401144346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}