{"id":"W4413922882","doi":"10.1101/2025.08.30.25334664","title":"Diagnostic Accuracy of CSF Tap-Test Parameters in Predicting Shunt Responsiveness in Normal Pressure Hydrocephalus: A Cohort Study","year":2025,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Cerebrospinal fluid and hydrocephalus","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Normal pressure hydrocephalus; Hydrocephalus; Medicine; Cohort; Shunt (medical); Internal medicine; Surgery; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001869234,0.0005383804,0.0006344942,0.001399298,0.0004975634,0.0009343046,0.0005359113,0.0005971264,0.001211538],"category_scores_gemma":[0.005887185,0.0003670886,0.0007606677,0.000868876,0.0005552528,0.0007924028,0.0006764054,0.0005734625,0.000284861],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002699186,"about_ca_system_score_gemma":0.0003650841,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002052488,"about_ca_topic_score_gemma":0.001390759,"domain_scores_codex":[0.9987502,0.0003329618,0.0001673054,0.0003499131,0.0002277036,0.0001718289],"domain_scores_gemma":[0.9969506,0.0008972323,0.0008619634,0.0004486241,0.0004249112,0.000416585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001913143,0.0000361957,0.9989459,0.000004523766,0.00006129286,0.00008218137,0.00003755608,0.00001779524,0.0001182974,0.000005188186,0.00002449054,0.0004752414],"study_design_scores_gemma":[0.00002014997,0.0003857626,0.9979601,0.000007056199,0.00008676862,0.0006648119,0.0001700129,0.0004695115,0.0001003522,0.00003177866,0.00009491556,0.000008789709],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996173,0.0001029208,0.00006738484,0.000006837517,0.000004251195,0.000009015621,0.00009994007,0.00000149553,0.00009081511],"genre_scores_gemma":[0.9997146,0.00003859543,0.00004952193,0.00000548432,0.000007093252,0.000008361545,0.0001484504,0.000001434117,0.00002647095],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002052488,"threshold_uncertainty_score":0.00988555,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02352765149449946,"score_gpt":0.2959248410847581,"score_spread":0.2723971895902586,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}