{"id":"W4413924692","doi":"10.1371/journal.pmen.0000346","title":"The effect of weight loss on brain age in schizophrenia spectrum disorders","year":2025,"lang":"en","type":"article","venue":"PLOS mental health.","topic":"Diet and metabolism studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Diabetes Canada; University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Schizophrenia spectrum; Schizophrenia (object-oriented programming); Weight loss; Neuroscience; Spectrum (functional analysis); Medicine; Psychology; Psychiatry; Audiology; Psychosis; Internal medicine; Physics; Obesity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005368804,0.0003632598,0.0003401289,0.0003318163,0.0001479652,0.0002342102,0.0001255489,0.000185403,0.000557796],"category_scores_gemma":[0.001448823,0.00009754289,0.0004112079,0.0001210313,0.0001673175,0.0002364609,0.0003223376,0.0003901394,0.00006588494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003599967,"about_ca_system_score_gemma":0.0002803654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006239237,"about_ca_topic_score_gemma":0.01319419,"domain_scores_codex":[0.9998662,0.00004469047,0.00001339564,0.00001892442,0.00003291245,0.0000238517],"domain_scores_gemma":[0.999715,0.00009001197,0.0000849621,0.00002535698,0.00002845974,0.00005614003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.04031642,0.002466103,0.4444893,0.0005099153,0.001475015,0.000387392,0.000380084,0.01015701,0.05353765,0.0002266486,0.0006285462,0.4454259],"study_design_scores_gemma":[0.0002498169,0.004719777,0.9834433,0.00005385936,0.0003038027,0.000173531,0.0001566441,0.007355337,0.002872168,0.0002794124,0.0003745402,0.00001782208],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987137,0.0007000704,0.0002479451,0.00006402186,0.000006026305,0.000009048099,0.00006390048,0.000006686288,0.000188549],"genre_scores_gemma":[0.9990103,0.0003703912,0.0003792681,0.00002622854,0.000003763133,0.000008201922,0.0001013803,0.000002478998,0.00009790449],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006239237,"threshold_uncertainty_score":0.01240581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006520253451222587,"score_gpt":0.2887007826284766,"score_spread":0.282180529177254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}