{"id":"W4413940624","doi":"10.1038/s44385-025-00020-2","title":"Self-assembled DNA nanocarrier-enabled drug delivery for bone remodeling and antimicrobial applications","year":2025,"lang":"en","type":"article","venue":"npj Biomedical Innovations.","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Institute of Musculoskeletal Health and Arthritis; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Nanocarriers; Drug delivery; Antimicrobial; Drug; Antimicrobial drug; Nanotechnology; Chemistry; Pharmacology; Medicine; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001219708,0.0002457232,0.0001652467,0.0001886535,0.0001169322,0.0001845268,0.0002390772,0.0003730276,0.0006853085],"category_scores_gemma":[0.0001492553,0.0001345838,0.0001813358,0.0001036818,0.0001880639,0.0002182429,0.0001874797,0.0002140893,0.0003063549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004463022,"about_ca_system_score_gemma":0.0003064034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007611191,"about_ca_topic_score_gemma":0.001392954,"domain_scores_codex":[0.9999037,0.00001098469,0.00000797627,0.00002649359,0.00003438559,0.00001648203],"domain_scores_gemma":[0.9999301,0.00001186823,0.00002180685,0.000004331001,0.00001636605,0.0000155645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001550678,0.000009186751,0.00003407321,0.00003391258,0.000002234596,0.00002715092,0.000008488646,0.0002319448,0.9978543,0.0001420695,0.00003471133,0.001606398],"study_design_scores_gemma":[0.000009437304,0.00008493971,0.0001757689,0.000003016355,0.000004953504,0.00006380757,0.000005717156,0.002569777,0.994625,0.00003629645,0.00241493,0.000006231577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9221581,0.006442146,0.0655771,0.0004353032,0.0001977326,0.0001701631,0.0003013753,0.0005320395,0.004185867],"genre_scores_gemma":[0.9481994,0.001090147,0.04546428,0.0001346138,0.00001664249,0.00008324433,0.0001547846,0.00002660644,0.004830384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007611191,"threshold_uncertainty_score":0.003238201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006394943454700319,"score_gpt":0.2706781877657664,"score_spread":0.264283244311066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}