{"id":"W4413951787","doi":"10.1016/j.neuron.2025.07.017","title":"Entangled cellular and molecular relationships at the sensory neuron-cancer interface","year":2025,"lang":"en","type":"review","venue":"Neuron","topic":"Cancer, Stress, Anesthesia, and Immune Response","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Queen's University","funders":"National Cancer Institute; Canadian Institutes of Health Research; Vetenskapsrådet; Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Natural Sciences and Engineering Research Council of Canada; Knut och Alice Wallenbergs Stiftelse; University of Wisconsin-Madison; Canadian Cancer Society; National Institutes of Health; University of Wisconsin Carbone Cancer Center; National Institute of Dental and Craniofacial Research; Canada Foundation for Innovation; Simons Foundation; American Cancer Society; Howard Hughes Medical Institute; U.S. Department of Defense","keywords":"Neuroscience; Interface (matter); Sensory system; Neuron; Cancer; Sensory neuron; Biology; Communication; Psychology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002015613,0.0004473679,0.001105336,0.0001699303,0.000203045,0.00004133159,0.0001926877,0.0002559337,0.0001521621],"category_scores_gemma":[0.000275743,0.0003133768,0.0004146744,0.0002768862,0.0001743192,0.00003613541,0.0001789119,0.0009577774,0.00007139408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000180357,"about_ca_system_score_gemma":0.0003308443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003067689,"about_ca_topic_score_gemma":0.00001159885,"domain_scores_codex":[0.9975725,0.0008085203,0.0004755386,0.0005768166,0.0002712792,0.0002952827],"domain_scores_gemma":[0.9980329,0.0007493963,0.0002350336,0.0008365897,0.00004524018,0.0001008709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004680385,0.0001033529,0.00009615672,0.02608923,0.0002929587,0.0005240893,0.0002262247,0.00000813515,0.001036008,0.00004397621,0.01261741,0.9584944],"study_design_scores_gemma":[0.0003828445,0.0001061993,0.0001319927,0.007292016,0.001693188,0.0002632491,0.00002024044,0.00001132406,0.0002542894,0.000002871055,0.989624,0.0002177339],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002576627,0.9933934,0.00001233293,0.0009032111,0.0005757541,0.001251285,0.00003146494,0.00006167845,0.001194233],"genre_scores_gemma":[0.0002275253,0.9737994,0.000006686359,0.0004092689,0.0002385324,0.0001378328,0.00003987127,0.00007843266,0.02506244],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9770066,"threshold_uncertainty_score":0.9999318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04304996894241592,"score_gpt":0.323308826275352,"score_spread":0.2802588573329361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}