{"id":"W4413965630","doi":"10.1182/bloodadvances.2025016915","title":"Harmonized immune recovery monitoring after HCT: evidence and practical guidance from the Westhafen Intercontinental Group","year":2025,"lang":"en","type":"article","venue":"Blood Advances","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"NIH Clinical Center; National Cancer Institute; Medac; Swedish Orphan Biovitrum; bluebird bio; Atara Biotherapeutics; Memorial Sloan-Kettering Cancer Center; Les Laboratories Pierre Fabre; Celgene; Sanofi; Bristol-Myers Squibb; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Immune system; Transplantation; Flow cytometry; Medicine; Hematopoietic cell; CD8; Immunology; Limiting; Oncology; Intensive care medicine; Haematopoiesis; Internal medicine; Stem cell; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002427295,0.0001463486,0.0002527122,0.00003298095,0.00007030085,0.00005617039,0.00007616355,0.00005709115,0.00003712628],"category_scores_gemma":[0.0003471948,0.0001035434,0.00006111609,0.0001223593,0.0000927745,0.0004770977,0.00004964504,0.0001959309,0.00001370941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002051888,"about_ca_system_score_gemma":0.00003898281,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007271302,"about_ca_topic_score_gemma":0.00002025971,"domain_scores_codex":[0.9989243,0.00007978787,0.0003238558,0.0003000755,0.0001952835,0.0001766654],"domain_scores_gemma":[0.9984524,0.00111231,0.00008090698,0.0002603768,0.00004429883,0.00004969409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001968706,0.0002574079,0.843478,0.0004621012,0.0002232229,0.0002789773,0.0009239785,8.208311e-7,0.1379281,0.000130675,0.00006216756,0.01428587],"study_design_scores_gemma":[0.00293091,0.0001977297,0.866708,0.008299126,0.0007965688,0.0002086611,0.0009375805,0.00002898358,0.1138285,0.0005409143,0.005302923,0.0002200747],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9378681,0.054142,0.002477017,0.004033196,0.0005879084,0.0003950278,0.000009340606,0.00005477271,0.0004326268],"genre_scores_gemma":[0.9816052,0.005846744,0.01165179,0.000266309,0.0001910028,0.00009453212,0.000006142016,0.00001243664,0.0003258644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04829526,"threshold_uncertainty_score":0.4222376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01957947992131258,"score_gpt":0.3121063447221091,"score_spread":0.2925268648007965,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}