{"id":"W4413969371","doi":"10.3389/fnsys.2025.1585367","title":"Neurobiology of psilocybin: a comprehensive overview and comparative analysis of experimental models","year":2025,"lang":"en","type":"article","venue":"Frontiers in Systems Neuroscience","topic":"Psychedelics and Drug Studies","field":"Psychology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia, Okanagan Campus; University of British Columbia; Acadia University","funders":"Research Nova Scotia","keywords":"Psilocybin; Neuroscience; Cognitive science; Computer science; Psychology; Hallucinogen; Psychiatry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001170342,0.001268578,0.00116434,0.002943552,0.0004560346,0.001031943,0.0008858517,0.0007935733,0.002127786],"category_scores_gemma":[0.0005878416,0.0003319764,0.0009903003,0.001512699,0.0009210589,0.001690017,0.0007553657,0.001656464,0.0008918823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001265094,"about_ca_system_score_gemma":0.001249855,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002024128,"about_ca_topic_score_gemma":0.002058682,"domain_scores_codex":[0.9997055,0.00004809005,0.00004298744,0.00007533516,0.00009000794,0.00003801922],"domain_scores_gemma":[0.999692,0.00006598994,0.00007562697,0.00003307328,0.00009171002,0.00004158863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001300843,0.0005608207,0.00631246,0.02134416,0.0005988303,0.001294774,0.0003316606,0.001164603,0.2101374,0.0160101,0.02078386,0.7201604],"study_design_scores_gemma":[0.0001754191,0.003306887,0.04092513,0.005958372,0.001944772,0.01196939,0.0004617965,0.002476925,0.1244288,0.01926475,0.7887715,0.0003163702],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01975138,0.9502266,0.01613861,0.001613872,0.0004102933,0.0002362804,0.001839965,0.0003138591,0.009469151],"genre_scores_gemma":[0.0448896,0.9394351,0.009702959,0.0006643139,0.0002677998,0.0004488879,0.002302883,0.00005291629,0.002235558],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002943552,"threshold_uncertainty_score":0.009178936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1316459934828702,"score_gpt":0.3896298073252606,"score_spread":0.2579838138423903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}