{"id":"W4413972241","doi":"10.1016/j.autrev.2025.103917","title":"The fragility of randomized controlled trials in large vessel vasculitis","year":2025,"lang":"en","type":"article","venue":"Autoimmunity Reviews","topic":"Vasculitis and related conditions","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Population Health Research Institute","funders":"","keywords":"Fragility; Vasculitis; Medicine; Randomized controlled trial; Cardiology; Internal medicine; Physics; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.4071236,0.002823899,0.01915349,0.004567722,0.002333204,0.009268849,0.004482912,0.01151401,0.01329853],"category_scores_gemma":[0.7340772,0.00290208,0.01823617,0.005621811,0.01021385,0.01477798,0.004773595,0.01507322,0.001560431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004975287,"about_ca_system_score_gemma":0.003997121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002985194,"about_ca_topic_score_gemma":0.003485699,"domain_scores_codex":[0.3662012,0.5576212,0.04462924,0.01366266,0.01514944,0.002736267],"domain_scores_gemma":[0.1047787,0.8444187,0.02317495,0.01877474,0.00684013,0.002012708],"domain_codex":"methods","domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"not_applicable","study_design_scores_codex":[0.1184057,0.0002933834,0.0127636,0.1411403,0.340881,0.001015301,0.00135362,0.00580878,0.0008924031,0.06088928,0.06841584,0.2481409],"study_design_scores_gemma":[0.2147086,0.008827966,0.02007288,0.07620218,0.2044433,0.00146168,0.0009127286,0.01767667,0.001191663,0.3220321,0.1316961,0.0007742904],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.01792917,0.7603429,0.06789768,0.08552011,0.04256216,0.004838669,0.002705344,0.00100058,0.01720337],"genre_scores_gemma":[0.684515,0.09207343,0.05905249,0.1140523,0.03411635,0.009377859,0.001718374,0.000897973,0.004196144],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.4071236,"threshold_uncertainty_score":0.7311221,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02872125587720603,"score_gpt":0.3435928619423383,"score_spread":0.3148716060651323,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}