{"id":"W4413994504","doi":"10.3324/haematol.2025.288332","title":"Caffeine impairs red blood cell storage quality by dual inhibition of ADORA2b signaling and G6PD activity","year":2025,"lang":"en","type":"article","venue":"Haematologica","topic":"Neonatal Health and Biochemistry","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute","keywords":"Caffeine; Red blood cell; Pharmacology; Medicine; Hematocrit; Hemolysis; Oxidative stress; Physiology; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028949,0.0001305889,0.0004326036,0.00004039587,0.00007037498,0.000005207942,0.00003115481,0.0001858234,0.00005216206],"category_scores_gemma":[0.0001301753,0.0001040734,0.00005712056,0.0001538841,0.0001116216,0.00003200806,0.00005583104,0.000198123,0.000001467032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002219974,"about_ca_system_score_gemma":0.00008716414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009169924,"about_ca_topic_score_gemma":0.000003812882,"domain_scores_codex":[0.9990033,0.00007234568,0.0002998023,0.0002675378,0.0001530236,0.0002040173],"domain_scores_gemma":[0.9993409,0.0001221894,0.0001551354,0.000188878,0.000066942,0.0001259497],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006786017,0.0005264925,0.004813071,0.003592998,0.00002313136,0.0001333544,0.00005086675,1.823055e-7,0.9871429,0.000048628,0.001975591,0.001014228],"study_design_scores_gemma":[0.001683183,0.0002855592,0.006049233,0.0002079363,0.00007762864,0.00008442776,0.0001673859,0.00001775076,0.9910564,0.0001128331,0.0001580707,0.00009956735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958059,0.001326511,0.00008366242,0.0009555848,0.00003373995,0.0002636943,0.00005796908,0.00005658931,0.001416399],"genre_scores_gemma":[0.9988815,0.00006724852,0.0003791062,0.0002400474,0.00001830547,0.000008235275,0.00005534872,0.000005054317,0.0003451096],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003913568,"threshold_uncertainty_score":0.4243989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0147338843730064,"score_gpt":0.2985393810672807,"score_spread":0.2838054966942744,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}