{"id":"W4414003707","doi":"10.1016/s2352-3018(25)00163-8","title":"Epstein–Barr virus and cytomegalovirus co-infections and mortality risk in patients with HIV-associated cryptococcal meningitis: a post-hoc analysis of a prospective nested cohort in the AMBITION-cm randomised controlled trial","year":2025,"lang":"en","type":"article","venue":"The Lancet HIV","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"European and Developing Countries Clinical Trials Partnership; Medical Research Council; National Institute of Allergy and Infectious Diseases; Foreign, Commonwealth and Development Office; National Research Foundation; National Institute of Neurological Disorders and Stroke; National Institute for Health and Care Research; Wellcome Trust; Styrelsen för Internationellt Utvecklingssamarbete; Department of Health and Social Care; Department of Science and Technology, Republic of South Africa; Wellcome","keywords":"Medicine; Post-hoc analysis; Cytomegalovirus; Nested case-control study; Prospective cohort study; Human immunodeficiency virus (HIV); Cohort; Cryptococcal meningitis; Cohort study; Meningitis; Randomized controlled trial; Pediatrics; Internal medicine; Virology; Viral disease; Herpesviridae","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006709229,0.001196398,0.00269483,0.0002994553,0.0003493115,0.001311577,0.0008636016,0.000986455,0.002020088],"category_scores_gemma":[0.008074516,0.0004691299,0.004912533,0.0003483661,0.0007703974,0.0006565683,0.0007680192,0.001977582,0.0001798821],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006372766,"about_ca_system_score_gemma":0.001193972,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001254781,"about_ca_topic_score_gemma":0.001937699,"domain_scores_codex":[0.9962058,0.002670697,0.0002512379,0.0003622445,0.0001764257,0.0003334369],"domain_scores_gemma":[0.9939275,0.002691723,0.001525472,0.0006757615,0.0004059382,0.0007736334],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9451786,0.001626025,0.0299331,0.001155826,0.01477912,0.0001037681,0.0001723303,0.000474557,0.001367744,0.0001240964,0.0004857728,0.004598919],"study_design_scores_gemma":[0.6205726,0.1525116,0.174954,0.0004722316,0.04189603,0.0002965531,0.0005207179,0.003920428,0.001985344,0.0006336181,0.00209128,0.0001454363],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964648,0.001972439,0.000176862,0.000129084,0.0001001076,0.0005325683,0.0003663622,0.000008318626,0.0002493471],"genre_scores_gemma":[0.9970475,0.0004159642,0.0005207768,0.0001299215,0.00009375525,0.0008592856,0.000516529,0.000004420273,0.0004118215],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006709229,"threshold_uncertainty_score":0.03548223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009319499436991356,"score_gpt":0.278624268363961,"score_spread":0.2693047689269697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}