{"id":"W4414011184","doi":"10.1371/journal.pgen.1011656","title":"Distinct cellular and reproductive consequences of meiotic chromosome synapsis defects in syce2 and sycp1 mutant zebrafish","year":2025,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Institute of General Medical Sciences","keywords":"Synapsis; Biology; Meiosis; Genetics; Zebrafish; Mutant; Chromosome segregation; Chromosome; Evolutionary biology; Cell biology; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008371082,0.0007136906,0.0003189873,0.000788766,0.0002257532,0.0002654355,0.0003487829,0.0006363447,0.001866619],"category_scores_gemma":[0.0001350331,0.000380801,0.0004768512,0.0001641283,0.0004710484,0.0002360001,0.0004791291,0.0008305209,0.00030687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005757795,"about_ca_system_score_gemma":0.0003916587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003747661,"about_ca_topic_score_gemma":0.006106958,"domain_scores_codex":[0.9998156,0.000008241856,0.00001785425,0.0000546866,0.00006091795,0.00004265028],"domain_scores_gemma":[0.9997934,0.00001698403,0.00007937623,0.00001192888,0.00001832769,0.00008003465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004059553,0.000005557848,0.0002467901,0.00001749139,0.000004041693,0.000210395,0.00001377962,0.00004868361,0.9990432,0.00008809699,0.00002187656,0.0002594463],"study_design_scores_gemma":[0.00006398733,0.0003576095,0.07391401,0.00002231405,0.0000638916,0.002488947,0.0001215574,0.001431931,0.9196655,0.0001934027,0.001636292,0.00004050305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960077,0.0006168212,0.001024322,0.00007609776,0.00001844788,0.00001778762,0.0009877834,0.00008189364,0.001169333],"genre_scores_gemma":[0.991772,0.0003683952,0.001184976,0.0000685524,0.000005976439,0.00005465938,0.0007515017,0.00006953818,0.005724347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003747661,"threshold_uncertainty_score":0.007451713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009067884244451763,"score_gpt":0.2231758735417026,"score_spread":0.2141079892972508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}