{"id":"W4414017062","doi":"10.1128/msystems.00847-25","title":"Modeling reveals a metabolic basis of competition among <i>Dehalobacter</i> strains during tandem chloroform and dichloromethane metabolism","year":2025,"lang":"en","type":"article","venue":"mSystems","topic":"Microbial Fuel Cells and Bioremediation","field":"Environmental Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Genome Canada","keywords":"Dichloromethane; Chloroform; Dehalococcoides; Reductive dechlorination; Enrichment culture; Strain (injury); Chemistry; Biology; Bacteria; Microbiology; Biodegradation; Biochemistry; Chromatography; Organic chemistry; Genetics; Solvent","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004451918,0.0001464934,0.0003360117,0.00008057589,0.0001035229,0.00003445218,0.0001269154,0.00009043331,0.0001207453],"category_scores_gemma":[0.0000233713,0.0001281631,0.00006779898,0.0003223633,0.00007932979,0.0001954962,0.0001107399,0.00008509215,0.00001069252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005314368,"about_ca_system_score_gemma":0.000006928262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001220919,"about_ca_topic_score_gemma":0.0004157904,"domain_scores_codex":[0.9988096,0.00005979434,0.0004154637,0.0002756191,0.0002148672,0.0002246968],"domain_scores_gemma":[0.9995915,0.0000136848,0.0001276425,0.0001805755,0.0000163524,0.0000702683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00001228627,0.00005137866,0.06304603,0.0002655391,0.00004452452,0.000001591577,0.0004581713,0.001552416,0.9331455,0.0006435922,0.00002762248,0.0007513344],"study_design_scores_gemma":[0.001550109,0.00003236257,0.8499491,0.0004147793,0.0002155656,0.000009420563,0.0005275465,0.01502521,0.1303798,0.0003433548,0.001090353,0.0004623805],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953095,0.0006854921,0.0006025119,0.00004316133,0.0002282091,0.0003275427,0.0000284901,0.00003039349,0.002744694],"genre_scores_gemma":[0.9990354,0.0003700325,0.0001440488,0.00002971121,0.0000619233,0.00001515319,0.00001643327,0.000009328252,0.000317962],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8027657,"threshold_uncertainty_score":0.5226339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006212604763856417,"score_gpt":0.1984944958055891,"score_spread":0.1922818910417327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}