{"id":"W4414029089","doi":"10.1101/2025.08.31.673361","title":"Keeping an Eye on Plasticity Genes: Insulin/TOR Pathway Components Mediating Nutritional Plasticity of Eyes Within and Between Sex","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Plasticity; Biology; Gene; Genetics; Insulin; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009110309,0.0004228139,0.0002437617,0.0002828524,0.0002006141,0.0003974297,0.0002835123,0.0002701318,0.002051287],"category_scores_gemma":[0.0001590621,0.0002283096,0.0002851616,0.0001396004,0.00025577,0.0002491244,0.0004853342,0.0005022936,0.0003412201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003621676,"about_ca_system_score_gemma":0.0001504598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007129806,"about_ca_topic_score_gemma":0.001200775,"domain_scores_codex":[0.9998758,0.00001311671,0.00001381359,0.00004727837,0.00003076837,0.00001917818],"domain_scores_gemma":[0.9997681,0.00003690815,0.00009505053,0.00002408857,0.0000283143,0.00004745621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004997913,0.000004101938,0.0004646707,0.000014711,0.000003212447,0.00002963496,0.000006595752,0.00003155179,0.9987877,0.0000266578,0.00001371803,0.0005675292],"study_design_scores_gemma":[0.00001719643,0.0001543062,0.1228667,0.00001626609,0.0000367436,0.0003161285,0.0001000813,0.002320077,0.8727509,0.00009415085,0.001311225,0.00001627536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953485,0.0006054473,0.002191896,0.00006684683,0.00001659992,0.00001404994,0.0005036938,0.00009699794,0.001155965],"genre_scores_gemma":[0.9967371,0.0001855194,0.000991625,0.00006124558,0.000004220552,0.00001829723,0.000266142,0.00003755399,0.001698351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002051287,"threshold_uncertainty_score":0.006862283,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0197409063285291,"score_gpt":0.2486778766558309,"score_spread":0.2289369703273018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}