{"id":"W4414034539","doi":"10.1080/08916934.2025.2551517","title":"Quantification of residual plasmid DNA and SV40 promoter-enhancer sequences in Pfizer/BioNTech and Moderna modRNA COVID-19 vaccines from Ontario, Canada","year":2025,"lang":"en","type":"article","venue":"Autoimmunity","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Plasmid; Virology; DNA; Enhancer; Biology; Molecular biology; Coronavirus disease 2019 (COVID-19); Genetics; Medicine; Gene; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001018135,0.00118359,0.000662472,0.001933505,0.0009317571,0.0008193069,0.0007071037,0.0005507111,0.002871613],"category_scores_gemma":[0.001430228,0.0005063009,0.0003448941,0.001631403,0.0009624266,0.0003754098,0.0005677687,0.0006896681,0.0008176013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005333847,"about_ca_system_score_gemma":0.005661052,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.2744016,"about_ca_topic_score_gemma":0.4696698,"domain_scores_codex":[0.9968961,0.0001078397,0.0001233702,0.0005453249,0.002002328,0.0003249423],"domain_scores_gemma":[0.9989202,0.0001053157,0.0001481162,0.0000516985,0.000678096,0.00009661369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000148057,0.00004583846,0.00410375,0.0001488635,0.000028322,0.00004797113,0.0002560077,0.000355088,0.9835608,0.0001428557,0.0004019218,0.01076055],"study_design_scores_gemma":[0.00001809259,0.0004113847,0.04091386,0.00006506059,0.00008280244,0.0001636935,0.0002204734,0.001718632,0.9378901,0.00007235711,0.01840783,0.00003561811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9047961,0.007013659,0.0501905,0.0003607058,0.00010128,0.001342988,0.02165985,0.001495296,0.01303964],"genre_scores_gemma":[0.7345338,0.006974723,0.1356088,0.0006059862,0.00004105573,0.001711005,0.06689503,0.001017458,0.05261216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7255983,"threshold_uncertainty_score":0.5456089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01783806268016042,"score_gpt":0.26515970313708,"score_spread":0.2473216404569196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}