{"id":"W4414039074","doi":"10.33696/pathology.6.057","title":"The Presence, Origins and Potential Role of Bi-hormonal Endocrine Cells Within the Pancreatic Islets of Langerhans","year":2025,"lang":"en","type":"article","venue":"Journal of Experimental Pathology","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Lawson Foundation","keywords":"Endocrine system; Hormone; Enteroendocrine cell; Pancreatic islets; Islet; Endocrinology; Pancreas; Internal medicine; Biology; Insulin; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003648943,0.000177668,0.000203175,0.0004380157,0.0002026578,0.001003255,0.0003104095,0.0002823596,0.0005285111],"category_scores_gemma":[0.0004216637,0.0001904727,0.0001705959,0.0003836925,0.000410969,0.0008254172,0.0005542962,0.0005023937,0.0003094961],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001862698,"about_ca_system_score_gemma":0.000221557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004414646,"about_ca_topic_score_gemma":0.0004241537,"domain_scores_codex":[0.9997872,0.00002749333,0.00001976493,0.00008322846,0.00004488315,0.00003743192],"domain_scores_gemma":[0.9995834,0.00008598984,0.0001181296,0.00006540815,0.00006677992,0.000080358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003060376,0.00002083861,0.02324695,0.0001316937,0.00001378248,0.0005210427,0.0003726906,0.00006192139,0.9610195,0.000919452,0.00004473495,0.01334145],"study_design_scores_gemma":[0.00001876634,0.0007336708,0.5395157,0.0001014151,0.0001424694,0.007285975,0.001882515,0.001079469,0.4263806,0.002167215,0.0206216,0.00007061995],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9760231,0.01764138,0.004379739,0.000178102,0.0000371783,0.00001200533,0.0002414169,0.00003469307,0.001452411],"genre_scores_gemma":[0.9869261,0.008112716,0.002668302,0.00009016795,0.00004310874,0.00001540786,0.0002643895,0.00001826009,0.001861676],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001003255,"threshold_uncertainty_score":0.00192982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00425957382549394,"score_gpt":0.255631117989137,"score_spread":0.251371544163643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}