{"id":"W4414039433","doi":"10.1016/j.hazmp.2025.100003","title":"Polystyrene nanoplastics target electron transport chain complexes in brain mitochondria","year":2025,"lang":"en","type":"article","venue":"Journal of Hazardous Materials Plastics","topic":"Microplastics and Plastic Pollution","field":"Environmental Science","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Laidlaw Foundation","keywords":"Polystyrene; Electron transport chain; Mitochondrion; Chain (unit); Chemistry; Electron; Biophysics; Cell biology; Biochemistry; Physics; Biology; Polymer; Organic chemistry; Nuclear physics; Quantum mechanics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001015721,0.0003614279,0.0001507424,0.0001721791,0.0001677036,0.00023535,0.00014812,0.0003836696,0.001251534],"category_scores_gemma":[0.0001856365,0.00009317588,0.0002151813,0.00008799451,0.0001477609,0.0002915346,0.0002303466,0.0002886684,0.0002824404],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002833415,"about_ca_system_score_gemma":0.0002231415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001302314,"about_ca_topic_score_gemma":0.001876586,"domain_scores_codex":[0.9999229,0.00001152088,0.000007124252,0.00001952917,0.00002228683,0.00001667587],"domain_scores_gemma":[0.9999235,0.00002140939,0.00001780781,0.00000575218,0.00001873,0.00001289807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005849834,0.00001012824,0.000129815,0.00008661611,0.000009403986,0.00005250142,0.00001561369,0.00006924255,0.9981804,0.00007807968,0.00004509804,0.001264579],"study_design_scores_gemma":[0.000004056076,0.0001739163,0.002568224,0.00001103219,0.00001697025,0.0001059105,0.0000335481,0.0004051942,0.9956362,0.00009780812,0.0009448953,0.00000231896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9787264,0.00923438,0.008571427,0.0002518276,0.0000892268,0.0000507618,0.0003165543,0.00006385746,0.002695633],"genre_scores_gemma":[0.9886217,0.00436394,0.003003833,0.000145451,0.00001930344,0.00003667211,0.0002622222,0.0000133777,0.003533412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001302314,"threshold_uncertainty_score":0.004186869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003910501113320504,"score_gpt":0.2114191752060127,"score_spread":0.2075086740926922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}