{"id":"W4414039699","doi":"10.1055/s-0045-1810778","title":"Long-term efficacy and safety of elafibranor in primary biliary cholangitis: Interim results from the open-label extension of the ELATIVE trial up to 3 years","year":2025,"lang":"en","type":"article","venue":"Zeitschrift für Gastroenterologie","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Interim; Open label; Medicine; Extension (predicate logic); Term (time); Interim analysis; Internal medicine; Gastroenterology; Clinical trial; Computer science; History; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007928083,0.001033043,0.003301134,0.0003494854,0.0007198378,0.001932506,0.0007809983,0.002401923,0.003732233],"category_scores_gemma":[0.005092063,0.0003897456,0.004335384,0.0004633801,0.001735799,0.002886995,0.0007674514,0.004062514,0.0009860802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009122464,"about_ca_system_score_gemma":0.0009925696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006041912,"about_ca_topic_score_gemma":0.0009450705,"domain_scores_codex":[0.9972699,0.00137498,0.000193575,0.000264623,0.000242888,0.0006540326],"domain_scores_gemma":[0.9939991,0.002222797,0.001361801,0.000926961,0.0003930165,0.001096251],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9413471,0.004056728,0.004162929,0.0004606552,0.001949217,0.000126534,0.0001199745,0.0006670956,0.003564561,0.0001572756,0.001099436,0.0422884],"study_design_scores_gemma":[0.6211886,0.2887058,0.06920987,0.0002913975,0.005984477,0.0004949055,0.0002217479,0.001086635,0.006018966,0.001205198,0.005453621,0.0001387307],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9799024,0.01196261,0.0009959835,0.001619592,0.0003593078,0.0004160214,0.002041738,0.00009877855,0.002603445],"genre_scores_gemma":[0.9902635,0.00199507,0.001099988,0.001443207,0.0005718966,0.000547365,0.002397171,0.0000281742,0.001653606],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007928083,"threshold_uncertainty_score":0.04192823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04432333310947916,"score_gpt":0.3372894813181284,"score_spread":0.2929661482086492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}