{"id":"W4414050061","doi":"10.1093/dote/doaf061.060","title":"435. CLINICAL RESPONSE IMPROVES THE PROGNOSTIC STRATIFICATION OF PATHOLOGICAL RESPONSE AFTER NEOADJUVANT CHEMOTHERAPY IN ESOPHAGEAL ADENOCARCINOMA","year":2025,"lang":"en","type":"article","venue":"Diseases of the Esophagus","topic":"Esophageal Cancer Research and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Pathological; Esophagectomy; Grading (engineering); Chemotherapy; Adenocarcinoma; Neoadjuvant therapy; Proportional hazards model; Esophageal adenocarcinoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008968133,0.0001499264,0.0002465204,0.0005934191,0.0001544922,0.0004497988,0.0001982798,0.0002802847,0.002152584],"category_scores_gemma":[0.002388868,0.0000735952,0.0003588933,0.0007752776,0.0001616419,0.0003154805,0.0002550543,0.0002339303,0.0004892307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002140585,"about_ca_system_score_gemma":0.0002033244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008713191,"about_ca_topic_score_gemma":0.001627097,"domain_scores_codex":[0.9995255,0.0001786795,0.00009687325,0.00007052419,0.00007443521,0.00005390832],"domain_scores_gemma":[0.9981713,0.000602156,0.0007526408,0.00008421571,0.000164629,0.0002250306],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003516035,0.00001796162,0.9961103,0.00001366911,0.00002101446,0.00004426442,0.000006489651,0.00009829552,0.0003379574,0.000006826764,0.0001151218,0.002876531],"study_design_scores_gemma":[0.00000728919,0.0001221198,0.9981951,0.000006602314,0.00002438075,0.0003206756,0.00003378871,0.0006792342,0.0002063074,0.00003026872,0.000371694,0.000002427033],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973949,0.0006392912,0.0001747157,0.00009140275,0.00001400392,0.000009390521,0.0008937123,0.000005530636,0.0007770474],"genre_scores_gemma":[0.9989058,0.00006736115,0.0001102329,0.00002087119,0.00001229542,0.000006001332,0.0007171706,0.000001735151,0.0001585756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002152584,"threshold_uncertainty_score":0.007201135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01688112945321067,"score_gpt":0.3477238325968713,"score_spread":0.3308427031436606,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}