{"id":"W4414053788","doi":"10.1021/acsomega.5c01294","title":"Application of Gene Editing Technology Based on Targeted Delivery Materials in TNBC","year":2025,"lang":"en","type":"review","venue":"ACS Omega","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University","funders":"Natural Science Foundation of Sichuan Province","keywords":"Genome editing; CRISPR; Cas9; RNA interference; Gene delivery; Genetic enhancement; Viral vector; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001355427,0.0002094749,0.0005553843,0.0003214522,0.00001469326,0.000005605561,0.0002411626,0.0004627402,0.000001868274],"category_scores_gemma":[0.0001022199,0.0002068683,0.00009182507,0.0003093469,0.00002460541,7.867104e-7,0.00007198145,0.0001062972,0.00000364028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002159231,"about_ca_system_score_gemma":0.0001003297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008864249,"about_ca_topic_score_gemma":0.000004245203,"domain_scores_codex":[0.9989979,0.00003161667,0.0003974326,0.0003319557,0.00006918106,0.0001719695],"domain_scores_gemma":[0.9993322,0.00002316704,0.000147286,0.0004375929,0.00004098616,0.00001869759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000149299,0.00007344461,0.00001975073,0.00951872,0.00007141042,0.000005502443,0.000003590157,0.0004779288,0.2061162,0.0000433622,0.0002668997,0.7833883],"study_design_scores_gemma":[0.0002758118,0.0001026225,0.00001376846,0.002593315,0.0001079486,0.000003732635,0.000006171037,0.00003860891,0.3833303,0.00001169577,0.6132194,0.0002966309],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002041047,0.9933345,0.003682172,0.00001366915,0.0001969351,0.0004757987,0.0001152339,0.00001789618,0.0001227907],"genre_scores_gemma":[0.03742796,0.9598085,0.001159253,0.00003044238,0.0001985109,0.000246675,0.00104126,0.00003365376,0.00005377943],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7830917,"threshold_uncertainty_score":0.8435846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006817038113877607,"score_gpt":0.2989180032281172,"score_spread":0.2921009651142396,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}