{"id":"W4414057044","doi":"10.1159/000548216","title":"Dramatic Inflammatory Regression of Choroidal Metastases from Renal Cell Carcinoma following Ipilimumab and Nivolumab Immunotherapy: A Case Series","year":2025,"lang":"en","type":"article","venue":"Ocular Oncology and Pathology","topic":"Ocular Oncology and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Nivolumab; Ipilimumab; Renal cell carcinoma; Collateral damage; Carcinoma; Melanoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003978528,0.001685721,0.001151935,0.001961407,0.002479203,0.001657154,0.001288631,0.004006933,0.00173183],"category_scores_gemma":[0.00218002,0.00117594,0.001350207,0.001212036,0.001866079,0.001629141,0.001381602,0.003194096,0.0009770665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001740346,"about_ca_system_score_gemma":0.0009955377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002931089,"about_ca_topic_score_gemma":0.004499228,"domain_scores_codex":[0.9991457,0.00009255579,0.00009189518,0.0002194736,0.0001477823,0.0003024995],"domain_scores_gemma":[0.9985625,0.0003054985,0.0003585134,0.0002097623,0.0001012012,0.0004625175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00003595084,0.000033723,0.00413759,0.00003384853,0.00001578196,0.9938312,0.0001505079,0.00003242858,0.0006492122,0.00005605686,0.0001363698,0.0008873645],"study_design_scores_gemma":[0.00001098522,0.00006117867,0.004550377,0.00001215868,0.00002164371,0.9942427,0.00009419073,0.0001250304,0.0003873798,0.00004083489,0.0004437141,0.000009821978],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9738928,0.0103738,0.003496405,0.001567467,0.0004112279,0.000286095,0.0002065324,0.0002530807,0.009512671],"genre_scores_gemma":[0.9951919,0.001851614,0.0007747956,0.0004196496,0.0005075645,0.00003640588,0.00008494688,0.00002102127,0.001112052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004006933,"threshold_uncertainty_score":0.01262718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008376254332711774,"score_gpt":0.2767380717488676,"score_spread":0.2683618174161558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}