{"id":"W4414081254","doi":"10.1111/apt.70360","title":"Prediction of Hepatocellular Carcinoma and Other Liver‐Related Events in Chronic Hepatitis B Patients With Metabolic Dysfunction or Metabolic Dysfunction‐Associated Steatotic Liver Disease","year":2025,"lang":"en","type":"article","venue":"Alimentary Pharmacology & Therapeutics","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"Stichting voor Lever- en Maag-Darm Onderzoek; Gilead Sciences","keywords":"Hepatocellular carcinoma; Cirrhosis; Incidence (geometry); Chronic hepatitis; Liver dysfunction; Risk factor; Chronic liver disease; Metabolic syndrome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007926491,0.0004008059,0.0003703082,0.0008623169,0.000279949,0.0005193551,0.0002969698,0.0004369262,0.001651836],"category_scores_gemma":[0.002595256,0.0002527189,0.0004213672,0.0007105573,0.0002121983,0.0003527697,0.0005308226,0.0004251838,0.0003252649],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002048365,"about_ca_system_score_gemma":0.000275986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003041572,"about_ca_topic_score_gemma":0.003683061,"domain_scores_codex":[0.9996488,0.0001530474,0.00003579344,0.0000504732,0.0000675915,0.00004434594],"domain_scores_gemma":[0.9986103,0.0003083881,0.0005761692,0.00005429504,0.0001293174,0.0003215337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00009248941,0.000009987047,0.9994295,0.00000313949,0.00001315763,0.00001534769,0.000006364617,0.00003064237,0.00003349409,0.00000261302,0.00002168499,0.0003416197],"study_design_scores_gemma":[0.00001365205,0.0001004468,0.9989234,0.000005703448,0.00001909901,0.000152444,0.0000452471,0.000640368,0.00003388936,0.00001808767,0.00004508132,0.000002470525],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994006,0.0001553003,0.00007354071,0.00002864198,0.000003853125,0.00000635468,0.0001311336,0.000002272967,0.0001983126],"genre_scores_gemma":[0.9994982,0.00006042435,0.0001000412,0.000009188566,0.00001048083,0.000004454743,0.0002463952,9.443638e-7,0.00006966324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003041572,"threshold_uncertainty_score":0.006047726,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02039867330445939,"score_gpt":0.255730190843956,"score_spread":0.2353315175394966,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}