{"id":"W4414084530","doi":"10.1161/strokeaha.125.052511","title":"Efficacy of Tenecteplase in Large Vessel Occlusion Stroke Within 24 Hours of Symptom Onset: The ETERNAL-LVO Randomized Controlled Trial","year":2025,"lang":"en","type":"article","venue":"Stroke","topic":"Acute Ischemic Stroke Management","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Tenecteplase; Randomized controlled trial; Stroke (engine); Occlusion; Fibrinolytic agent; Vascular disease; Thrombolysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003218959,0.001074804,0.002449389,0.0004002141,0.0003152691,0.001001794,0.0007872303,0.001454799,0.005812369],"category_scores_gemma":[0.003413089,0.0003359999,0.00190361,0.0003582901,0.0007062003,0.001085324,0.000456458,0.001691153,0.0005446743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004632602,"about_ca_system_score_gemma":0.0009051093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005026069,"about_ca_topic_score_gemma":0.001250802,"domain_scores_codex":[0.9984988,0.0009982882,0.0001202152,0.0001645075,0.00009620599,0.0001220672],"domain_scores_gemma":[0.9987718,0.0004573427,0.0003838089,0.0001040122,0.00008693249,0.0001960437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9884171,0.001514234,0.0006135093,0.0008236623,0.0008841007,0.00003452815,0.00002186214,0.0001436666,0.0005419046,0.0001510288,0.0005402606,0.006314205],"study_design_scores_gemma":[0.9817063,0.01405635,0.001988941,0.0000906772,0.0007276275,0.00003110413,0.00001317338,0.0003442132,0.0001818488,0.0001654943,0.0006816926,0.00001251793],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.967475,0.01637501,0.001476268,0.00137682,0.0009768793,0.00560275,0.002160201,0.0001423269,0.004414738],"genre_scores_gemma":[0.9694389,0.005887153,0.002662849,0.001672152,0.0008688688,0.01182002,0.002055633,0.00003842607,0.005556032],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005812369,"threshold_uncertainty_score":0.01944435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0073265818791387,"score_gpt":0.2705238966456732,"score_spread":0.2631973147665345,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}