{"id":"W4414089718","doi":"10.51731/cjht.2025.1220","title":"Guselkumab (Tremfya)","year":2025,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Reimbursement; Drug; Crohn disease; Public health; Disease; Crohn's disease","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002615674,0.0002866775,0.0005170546,0.0004666252,0.000311791,0.0004518045,0.0003704368,0.0006286767,0.01218662],"category_scores_gemma":[0.0003690764,0.00009255007,0.0004901995,0.0003996352,0.0002448988,0.0003630698,0.000391033,0.001917111,0.006875854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00102413,"about_ca_system_score_gemma":0.0007228264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002726617,"about_ca_topic_score_gemma":0.005912653,"domain_scores_codex":[0.9998228,0.00002322852,0.00001087566,0.00003068871,0.00004762844,0.00006481087],"domain_scores_gemma":[0.9998611,0.00001855746,0.00002630385,0.000009873506,0.0000214358,0.00006268491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006945709,0.001393614,0.003810296,0.001589146,0.0004220283,0.00218239,0.00008886569,0.0007372577,0.02330587,0.004265917,0.1435553,0.8117036],"study_design_scores_gemma":[0.01298811,0.00806194,0.03996425,0.001026382,0.0006178442,0.02145308,0.000125105,0.001568693,0.02417117,0.004136952,0.8857586,0.0001277719],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.3600279,0.3476018,0.00670721,0.02652735,0.003388688,0.0009763197,0.01101993,0.004253096,0.2394976],"genre_scores_gemma":[0.8229439,0.05736602,0.005302934,0.01010214,0.0006276806,0.0005242793,0.01166542,0.000133954,0.09133373],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.01218662,"threshold_uncertainty_score":0.04076827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01239833022196209,"score_gpt":0.2866926554622162,"score_spread":0.2742943252402542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}