{"id":"W4414125461","doi":"10.7573/dic.2025-5-2","title":"Treatment of vitiligo with topical ruxolitinib: a narrative review","year":2025,"lang":"en","type":"review","venue":"Drugs in Context","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Vitiligo; Ruxolitinib; Adverse effect; Tolerability; Calcineurin; Narrative review; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006879988,0.0002343102,0.0009529248,0.00004895008,0.00001658023,0.000004831512,0.0001166089,0.0001612837,0.000037131],"category_scores_gemma":[0.00003622781,0.0001607941,0.0002100551,0.00009449666,0.00004985983,0.000001196856,0.00002646215,0.00005845869,0.000004436413],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004763462,"about_ca_system_score_gemma":0.0002966542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002418644,"about_ca_topic_score_gemma":0.00005545673,"domain_scores_codex":[0.998873,0.0001792859,0.000416628,0.0003150604,0.00008784704,0.0001281944],"domain_scores_gemma":[0.9993834,0.00005933491,0.0001820169,0.0003025404,0.00004073732,0.00003191942],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002188434,0.00009622868,0.000009467778,0.0163628,0.0001157935,0.00000590777,0.0002868344,3.337269e-8,0.000005086755,0.0002257744,0.0007596494,0.9821106],"study_design_scores_gemma":[0.0004791886,0.0004291313,0.000001762874,0.02550819,0.0001936626,0.00001140376,0.0002777314,1.902128e-7,0.0001961635,0.000005698913,0.9727431,0.0001537929],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001620959,0.9947246,0.00001612515,0.0000390009,0.00007337259,0.0008780741,0.00004723305,0.000003107946,0.004056348],"genre_scores_gemma":[0.0004180213,0.9964681,0.00007346547,0.0001085492,0.00006766995,0.000307523,0.0005173603,0.00001186496,0.002027447],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9819567,"threshold_uncertainty_score":0.6556991,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02248872227859463,"score_gpt":0.3547900154546652,"score_spread":0.3323012931760706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}