{"id":"W4414152894","doi":"10.1016/j.ijantimicag.2025.107613","title":"Results of TOR001: An open-label single patient study using targeted bacteriophage therapy for the treatment of chronic urinary tract infection","year":2025,"lang":"en","type":"article","venue":"International Journal of Antimicrobial Agents","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph; University of Toronto; McMaster University; St Joseph's Health Centre","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Tolerability; Adverse effect; Urinary system; Clinical trial; Bacteriophage; Antibiotics; Phage therapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001940194,0.001257296,0.003464294,0.0002763304,0.000542642,0.00143579,0.0006640191,0.001743296,0.003926384],"category_scores_gemma":[0.001879928,0.0003599464,0.002234134,0.0003353047,0.001388738,0.001106368,0.000297466,0.002856621,0.0007432076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006835972,"about_ca_system_score_gemma":0.001557856,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009333934,"about_ca_topic_score_gemma":0.001997704,"domain_scores_codex":[0.9989748,0.0005999652,0.00006018303,0.0001224289,0.00008845412,0.0001541983],"domain_scores_gemma":[0.9985272,0.0005515181,0.0002580603,0.0001531651,0.0000953061,0.0004147462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"case_report","study_design_scores_codex":[0.7693159,0.05207301,0.003947004,0.00185698,0.002400016,0.0004933531,0.0003765763,0.001614928,0.04293394,0.0004301148,0.002460421,0.1220977],"study_design_scores_gemma":[0.1642986,0.8089289,0.01562479,0.0001225201,0.001317561,0.0005711744,0.0001996329,0.001168007,0.004548936,0.0001961787,0.002930246,0.00009358866],"study_design_candidate":"case_report","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917653,0.002375096,0.001548121,0.0004911294,0.0001934496,0.00103108,0.001062793,0.00008690855,0.001446029],"genre_scores_gemma":[0.9915622,0.002213071,0.001860521,0.0008253814,0.0002383323,0.0006909143,0.001096174,0.00004706949,0.001466356],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003926384,"threshold_uncertainty_score":0.01313508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05107010998984233,"score_gpt":0.3465863702936324,"score_spread":0.29551626030379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}