{"id":"W4414161912","doi":"10.4088/pcc.25nr03970","title":"Toward Precision Psychiatry","year":2025,"lang":"en","type":"article","venue":"The Primary Care Companion For CNS Disorders","topic":"Treatment of Major Depression","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Precision medicine; MEDLINE; Matching (statistics); Component (thermodynamics)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01900532,0.001133944,0.001696184,0.00208348,0.001566228,0.007444069,0.002472716,0.005674214,0.009047505],"category_scores_gemma":[0.02643535,0.0006683905,0.001589581,0.001062574,0.0102948,0.006782495,0.005551936,0.01183255,0.005030017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004442703,"about_ca_system_score_gemma":0.007840292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002667631,"about_ca_topic_score_gemma":0.002403453,"domain_scores_codex":[0.992349,0.003604692,0.0003958636,0.001085525,0.002120411,0.0004446262],"domain_scores_gemma":[0.9799897,0.01142301,0.000964185,0.003426254,0.003063826,0.00113303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001850116,0.0001286595,0.001713002,0.002096504,0.0002990367,0.0004184911,0.001155694,0.00202994,0.002420145,0.5744921,0.1095514,0.30551],"study_design_scores_gemma":[0.00008563288,0.0001653682,0.0008838193,0.001665242,0.0001034646,0.0004927011,0.0005660647,0.001628742,0.001719473,0.5431388,0.4494721,0.00007859255],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.005415297,0.2356106,0.2587947,0.3963207,0.0152457,0.0002660662,0.001298031,0.002690449,0.08435847],"genre_scores_gemma":[0.2285308,0.2547392,0.2963164,0.164978,0.02431898,0.001265447,0.001796749,0.001107228,0.02694711],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01900532,"threshold_uncertainty_score":0.100511,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01576729291961585,"score_gpt":0.2855342711694934,"score_spread":0.2697669782498776,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}