{"id":"W4414164306","doi":"10.34133/research.0867","title":"Gut Commensal Antibiotic-Resistant <i>Parabacteroides goldsteinii</i> Ameliorates Mouse Colitis through Valine–Isobutyrate Metabolism","year":2025,"lang":"en","type":"article","venue":"Research","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"MD Precision (Canada)","funders":"Central Public-interest Scientific Institution Basal Research Fund, Chinese Academy of Fishery Sciences; Natural Science Foundation of Shandong Province; National Natural Science Foundation of China","keywords":"Colitis; Ulcerative colitis; Gut flora; Inflammatory bowel disease; Metabolism; Receptor; Intestinal mucosa; Mediator; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009775518,0.0002379626,0.0003454805,0.000152438,0.0004095648,0.0001666207,0.000497268,0.0002662496,0.00003845308],"category_scores_gemma":[0.0001779319,0.0002200077,0.000122186,0.0004824651,0.0003389865,0.00001162943,0.0004193518,0.0004195337,0.0001082406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005428256,"about_ca_system_score_gemma":0.0004814533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006422931,"about_ca_topic_score_gemma":0.0002504285,"domain_scores_codex":[0.9972343,0.0005269015,0.0003945807,0.0006179624,0.0002911105,0.0009351781],"domain_scores_gemma":[0.9984509,0.00008457469,0.00006612533,0.0007366422,0.0005089605,0.0001528132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003089061,0.000144411,0.000538125,0.0001317584,0.0000858812,0.00001031511,0.00006554105,0.000002673472,0.9398577,0.002700071,0.05581305,0.0003415287],"study_design_scores_gemma":[0.000933855,0.0002357,0.008038725,0.00006709545,0.00001859138,0.000005471967,0.0002777163,0.00001104088,0.7333532,0.0003005616,0.2565306,0.000227404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871172,0.004237776,0.0001041786,0.00244137,0.0002170928,0.000511217,0.0002440972,0.00003534352,0.005091691],"genre_scores_gemma":[0.9813648,0.003085427,0.0007754241,0.001162434,0.0002598212,0.00002167406,0.000258063,0.00003929774,0.01303308],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2065045,"threshold_uncertainty_score":0.8971654,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04726917529920052,"score_gpt":0.3904718889494008,"score_spread":0.3432027136502003,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}